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Found 71 clinical trials
Enhanced Recovery After Surgery in Kidney Transplant Donors

transplant donors are typically healthy individuals who undergo laparoscopic nephrectomy. The most significant hindrance to discharge to return to activities of daily living is frequently return of bowel

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
Prairie Loin Pain Hematuria Syndrome Renal Denervation Study: A Feasibility Study

LPHS is opioid prescription and in some extreme cases, surgical denervation of the nociceptive impulses with renal auto transplantation and auto nephrectomy. Radiofrequency nerve ablation is a

  • 15 views
  • 10 May, 2022
  • 1 location
89Zr-DFO-Atezolizumab ImmunoPET/CT in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma

to immune checkpoint inhibitor therapy in patients with RCC. There will be two cohorts, one made up of patients with localized RCC who will undergo 89Zr-DFO-Atezolizumab PET/CT prior to nephrectomy

programmed cell death 1 ligand 1
pet scan
pd-l1
metastatic renal cell carcinoma
atezolizumab
  • 0 views
  • 21 Mar, 2022
  • 1 location
[18F]PT2385 PET/CT in Patients With Renal Cell Carcinoma

HIF2 immunohistochemistry (IHC). There will be two cohorts. The first pre-surgical cohort will have [18F]PT2385 PET/CT prior to nephrectomy. The uptake and retention on Positron Emission Tomography

pet scan
nephrectomy
immunohistochemistry
metastasis
carcinoma
  • 0 views
  • 03 Sep, 2021
  • 1 location
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer the PROBE Trial

cell growth. Surgery to remove the kidney, called a nephrectomy, is also considered standard of care; however, doctors who treat kidney cancer do not agree on its benefits. It is not yet known if the

  • 37 views
  • 18 Nov, 2021
  • 228 locations
Protocol Active Surveillance Small Renal Masses (SRMs)

renal tumorectomy / radical nephrectomy.

renal neoplasm
nephrectomy
hypercalcemia
metastasis
  • 3 views
  • 27 Feb, 2022
  • 1 location
CYTO Reductive Surgery in Kidney Cancer Plus Immunotherapy and Targeted Kinase Inhibition (Cyto-KIK)

The purpose of this study is to determine if the use of immunotherapy nivolumab and the targeted therapy cabozantinib prior to removal of the kidney, will increase the number subjects who are without any visible kidney cancer in their body at some point during the course of treatment.

heparin
pet scan
cancer
targeted therapy
metastatic renal cell carcinoma
  • 42 views
  • 22 Apr, 2022
  • 2 locations
Lenvatinib and Everolimus in Renal Cell Carcinoma (RCC)

The purpose of this research study is to see what effect the combination of lenvatinib plus everolimus has in local and metastatic renal cell carcinoma to potentially make surgically unresectable tumors resectable.

angiogenesis
metastatic renal cell carcinoma
tyrosine
VEGFR2
renal function tests
  • 0 views
  • 12 May, 2022
  • 1 location
STRONG for Surgery & Strong for Life - Against All Odds: Intensive Prehabilitation for Risk Reduction in Cancer Surgery (STRONG-CS)

Despite knowledge about the effect of preventive measures in lifestyle, smoking,nutrition, alcohol and physical activity (SNAP), there is a lack of systematic assessment of the overall lifestyle of the patient before surgery and knowledge about how lifestyle interventions can be organized in connection with cancer surgery. The intention with prehabilitation …

  • 0 views
  • 01 May, 2022
A Study of Combination Spartalizumab and Canakinumab in Patients With Localized Clear Cell Renal Cell Carcinoma (SPARC-1)

Primary Objective: To confirm the safety and feasibility of canakinumab and spartalizumab (PDR-001) administered using a standard dose / schedule in the neo-adjuvant setting in renal cell carcinoma Secondary Objectives: To assess the immune response to combination canakinumab and spartalizumab To assess anti-tumor activity as measured by pathologic downstaging

nephrectomy
carcinoma
neutrophil count
clear cell renal cell carcinoma
  • 1 views
  • 25 May, 2022