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Found 68 clinical trials
Comparison of OpeN VErsus RoboTic Partial Nephrectomy (CONVERT)

A prospective randomized controlled feasibility trial for patients undergoing partial nephrectomy for T1 renal masses at Princess Margaret. Participants will be randomized receive either open or

  • 0 views
  • 05 May, 2022
  • 1 location
A Comparative Study Between Analgesic Effect of Opioid Free and Opioid Based Anesthesia in Radical Nephrectomy Surgery

Patients undergoing nephrectomy have a high incidence of postoperative pain. In the perioperative period, these patients are often treated with patient-controlled opioids, epidural analgesia, or

Accepts healthy volunteers
  • 0 views
  • 30 May, 2022
  • 1 location
Auriculotherapy in the Treatment of Pre-Operative Anxiety

establish a superior correlation between the auriculotherapy treatment and the reduction of perioperative anxiety. Subject population will include those having a partial or total nephrectomy for cancer

Accepts healthy volunteers
  • 0 views
  • 22 Mar, 2022
  • 1 location
3D Printing for Pre-Surgical Planning (3D)

nephrectomy. 2) Compare the accuracy of this innovative method for 3D printing to radiological images and pathological data when available.

  • 0 views
  • 24 Mar, 2022
  • 2 locations
Microwave Ablation With MRI-Guided SBRT Boost in Renal Cell Carcinoma

The specific aims of this study are: To determine the safety and feasibility of treating patients with a combination of MRI guided stereotactic body radiation therapy and microwave ablation. To assess short and long-term toxicity rates of patients treated with a combined modality approach. To assess local control, survival, and …

primary tumor
metastasis
carcinoma
  • 6 views
  • 27 Jan, 2022
  • 1 location
A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)

treatment of Clear Cell Renal Cell Carcinoma (ccRCC) post nephrectomy. The primary study hypothesis is that belzutifan plus pembrolizumab is superior to placebo plus pembrolizumab with respect to

pembrolizumab
carcinoma
cancer
nephrectomy
primary tumor
  • 1 views
  • 29 Jul, 2022
  • 118 locations
Anesthesia and Cancer Study: Renal Cell Carcinoma

This study investigates the influence of type of anesthesia on recurrence and survival of renal cell carcinoma in patients undergoing nephrectomy. The participants will be allocated to either

nephrectomy
anesthesia
carcinoma
cancer
  • 1 views
  • 21 Mar, 2022
  • 1 location
Renal Adjuvant MultiPle Arm Randomised Trial (RAMPART)

RATIONALE: The current global standard of care after nephrectomy for localised RCC therefore remains active monitoring (i.e., observation by clinical and radiological means). 30-40% patients

platelet count
serum pregnancy test
systemic therapy
corticosteroids
carcinoma
  • 60 views
  • 14 Feb, 2022
  • 35 locations
Study of Oral Infigratinib for the Adjuvant Treatment of Subjects With Invasive Urothelial Carcinoma With Susceptible FGFR3 Genetic Alterations

nephrectomy. Study treatment is randomized 1:1 between infigratinib or placebo with treatment up to 1 year or until invasive local, distal, or metastatic disease recurrence confirmed by independent imaging

  • 97 views
  • 16 May, 2022
  • 130 locations
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

This phase II trial studies how well combination chemotherapy works in treating patients with newly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens such as UH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, and irinotecan) and …

  • 0 views
  • 30 May, 2022
  • 92 locations