Found 65 clinical trials
Comparison of OpeN VErsus RoboTic Partial Nephrectomy (CONVERT)
A prospective randomized controlled feasibility trial for patients undergoing partial nephrectomy for T1 renal masses at Princess Margaret. Participants will be randomized receive either open or
- 0 views
- 05 May, 2022
- 1 location
Auriculotherapy in the Treatment of Pre-Operative Anxiety
establish a superior correlation between the auriculotherapy treatment and the reduction of perioperative anxiety. Subject population will include those having a partial or total nephrectomy for cancer
- 0 views
- 22 Mar, 2022
- 1 location
3D Printing for Pre-Surgical Planning (3D)
nephrectomy. 2) Compare the accuracy of this innovative method for 3D printing to radiological images and pathological data when available.
- 0 views
- 24 Mar, 2022
- 2 locations
Microwave Ablation With MRI-Guided SBRT Boost in Renal Cell Carcinoma
The specific aims of this study are: To determine the safety and feasibility of treating patients with a combination of MRI guided stereotactic body radiation therapy and microwave ablation. To assess short and long-term toxicity rates of patients treated with a combined modality approach. To assess local control, survival, and …
- 6 views
- 27 Jan, 2022
- 1 location
Anesthesia and Cancer Study: Renal Cell Carcinoma
This study investigates the influence of type of anesthesia on recurrence and survival of renal cell carcinoma in patients undergoing nephrectomy. The participants will be allocated to either
- 1 views
- 21 Mar, 2022
- 1 location
A Multicenter, Double-blind, Randomized Phase 3 Study to Compare the Efficacy and Safety of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab, in the Adjuvant Treatment of Clear Cell Renal Cell Carcinoma (ccRCC) Post Nephrectomy (MK-6482-022)
treatment of Clear Cell Renal Cell Carcinoma (ccRCC) post nephrectomy. The primary study hypothesis is that belzutifan plus pembrolizumab is superior to placebo plus pembrolizumab with respect to
- 1 views
- 28 Oct, 2022
- 189 locations
Renal Adjuvant MultiPle Arm Randomised Trial (RAMPART)
RATIONALE: The current global standard of care after nephrectomy for localised RCC therefore remains active monitoring (i.e., observation by clinical and radiological means). 30-40% patients
- 60 views
- 14 Feb, 2022
- 35 locations
The Impact of Deep Versus Standard Muscle Relaxation on Intra-operative Safety During Laparoscopic Surgery: a Multicenter Strategy Study (EURORELAX)
Muscle relaxants are routinely applied during anesthesia to facilitate endotracheal intubation and to improve surgical working conditions. Several investigations have shown that a deep neuromuscular block (NMB) improves the surgical working conditions over a moderate NMB and effectively precludes sudden deterioration of the surgical field. However, whether the improvement of …
- 11 views
- 21 Oct, 2022
- 5 locations
Treatment of Newly Diagnosed Diffuse Anaplastic Wilms Tumors (DAWT) and Relapsed Favorable Histology Wilms Tumors (FHWT)
This phase II trial studies how well combination chemotherapy works in treating patients with newly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens such as UH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, and irinotecan) and …
- 0 views
- 28 Oct, 2022
- 95 locations
Anesthesia and Acute Kidney Injury After Nephrectomy
This study investigates the influence of type of anesthesia on postoperative renal dysfunction in patients undergoing nephrectomy. The participants will be allocated to either the group
- 0 views
- 04 Oct, 2022