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Found 127 clinical trials
Safety Tolerability and Pharmacokinetic Profile of SYL1801 Eye Drops

Study of the safety, tolerability and pharmacokinetic profile of different doses of SYL1801 eye drops in healthy volunteers.

  • 0 views
  • 04 Apr, 2021
  • 1 location
BEOVU Versus Eylea in the Treatment of Age-related Macular Neovascular Degeneration

Age-Related macular neovascularization degeneration occur is a vision threatening condition. The investigators compare the efficacy of BEOVU and Eylea intravitreal treatment in the management

  • 0 views
  • 24 May, 2021
  • 1 location
Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Chinese Patients With Neovascular Age-Related Macular Degeneration

To compare brolucizumab to aflibercept in Chinese patients with untreated active choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD)

aflibercept
brolucizumab
neovascularization
age-related macular degeneration
  • 2 views
  • 05 May, 2021
  • 14 locations
Ranibizumab Versus PDT for Presumed Ocular Histoplasmosis

The purpose of this study is to evaluate the change in visual activity of ranibizumab to Photodynamic Therapy (PDT)in patients with choroidal neovascularization (CNV) secondary to

  • 22 views
  • 07 Nov, 2020
  • 1 location
Clinical Study on the Treatment of Mixed Component Cornea for High Risk Keratoplasty

neovascularization after ocular trauma or infection, the graft rejection rate is more than 65%, it is called high-risk keratoplasty. This study will observe the graft survival of high-risk corneal

  • 0 views
  • 25 Jan, 2021
  • 1 location
TMZ Plus Apatinib in Newly Diagnosed High-grade Glioma RCT

grade glioma (HGG) is still poor.On the basis of a lot of exploration, the union medication has become a hot spot. Malignant glioma has obvious neovascularization and inhibiting angiogenesis can inhibit

blood transfusion
temozolomide
recurrent glioma
brain tumor
malignant glioma
  • 8 views
  • 22 Jan, 2021
  • 1 location
Pivotal 1 Study of RGX-314 Gene Therapy in Participants With nAMD

RGX-314 is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD). Wet AMD is characterized by loss of vision due to new, leaky blood vessel formation in the retina. Wet AMD is a significant cause of vision loss in the …

  • 0 views
  • 19 Sep, 2021
  • 8 locations
Photodynamic Therapy Combined With Bevacizumab vs Bevacizumab Alone for Neovascular Age-Related Macular Degeneration

alone or combined with PDT at the standard fluence rate, in patients with all types of choroidal neovascularization secondary to AMD. Hypothesis: bevacizumab in combination with PDT (low and

photodynamic therapy
age-related macular degeneration
visudyne
neovascularization
avastin
  • 17 views
  • 07 Nov, 2020
  • 1 location
RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Diabetic Retinopathy (DR) Without Center Involved-Diabetic Macular Edema (CI-DME)

is a sight-threatening disease characterized in the early stages by neuronal and vascular dysfunction in the retina, and later by neovascularization that leads to further deterioration of functional

background diabetic retinopathy
proliferative diabetic retinopathy
visual loss
diabetes
neovascularization
  • 0 views
  • 27 Jan, 2021
  • 7 locations
Study of Brolucizumab in Adult Patients With Suboptimal Anatomically Controlled Neovascular Age-related Macular Degeneration

Neovascular age-related macular degeneration is characterized by the presence of choroidal neovascularization (CNV), which consists of abnormal blood vessels originating from the choroid that

  • 0 views
  • 16 Aug, 2021
  • 48 locations