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Found 129 clinical trials
The Sahlgrenska Anti-VEGF Study

The study investigates whether patients treated for neovascular (wet) age-related macular degeneration (AMD), with intravitreal injection with bevacizumab (Avastin) after two years need more injections with retained therapy response compared to patients being treated with intravitreal injection with aflibercept (Eylea). The study also aims to evaluate if there is a …

  • 0 views
  • 04 Feb, 2021
  • 1 location
Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular Degeneration

Evaluate the safety, tolerability, and efficacy of OTX-TKI for intravitreal use in subjects with Neovascular Age-Related Macular Degeneration

  • 0 views
  • 15 Aug, 2021
  • 5 locations
Embolization of Middle Meningeal Artery in Chronic Subdural Hematoma

Chronic subdural hematoma (cSDH) is a common neurological affliction which affects mostly frail and elderly patients. Surgical evacuation by using burr hole craniostomy (BHC) is the most frequently used treatment but carries a recurrence rate varying between 10-30% in the literature. Especially in this frail population re-operation is undesirable. Embolization …

  • 0 views
  • 14 Jun, 2021
  • 1 location
Subretinal Macugen for Neovascular Age-Related Macular Degeneration

The purpose of this study is to assess the efficacy of pegaptanib (Macugen®) for neovascular (exudative) age-related macular degeneration (AMD) when the first dose is administered to the submacular space instead of vitreous body in cases when previous state-of-the-art treatment for the AMD was deemed ineffective.

age-related macular degeneration
fluorescein angiography
macugen
wet age-related macular degeneration
angiography
  • 20 views
  • 07 Nov, 2020
  • 1 location
Study of Intravitreal Microplasmin in Relieving Vitreo-Macular Adhesion in Neovascular Age-related Macular Degeneration

The purpose of this study is to determine whether microplasmin given by intravitreal injection is effective and safe for the treatment of wet age-related macular degeneration (AMD) in patients who have focal vitreomacular adhesion (VMA)

age-related macular degeneration
choroidal neovascular membrane
wet age-related macular degeneration
  • 32 views
  • 08 Nov, 2020
  • 1 location
Treatment of Patients With Neovascular AMD Using Indocyanine Green-Mediated Photothrombosis (i-MP).

To establish the safety and efficacy of indocyanine green-mediated photothrombosis (i-MP) for the treatment of patients with neovascular age-related macular degeneration.

neovascularization
age-related macular degeneration
indocyanine green
fluorescein angiography
wet age-related macular degeneration
  • 22 views
  • 07 Nov, 2020
  • 1 location
Bevacizumab and Photodynamic Therapy in Neovascular Age Related Macular Degeneration

The purpose of this study is to determine if of combination therapy of intravitreal bevacizumab 4 days after the application of photodynamic therapy could improve the visual outcomes of patients with neovascular age related macular degeneration.

age-related macular degeneration
photodynamic therapy
corrected visual acuity
bevacizumab
verteporfin
  • 17 views
  • 07 Nov, 2020
  • 1 location
Pilot Study to Evaluate the Safety and Efficacy of Treatment With ORA102 Combined With Avastin (Bevacizumab) Versus Avastin Alone in Patients With Neovascular Age Related Macular Degeneration (AMD)

This is s randomized, multi-center, double blind, 3 arm, phase I/II pilot study to evaluate the safety and efficacy of treatment with ORA102 combined with Avastin (Bevacizumab) versus Avastin alone, in patients with neo-vascular age related macular degeneration (AMD).

corrected visual acuity
bevacizumab
age-related macular degeneration
avastin
  • 30 views
  • 07 Nov, 2020
  • 1 location
A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD)

This Phase 3 study will evaluate the efficacy and safety of KSI-301 compared to aflibercept, in participants with neovascular (wet) age-related macular degeneration (wAMD)

  • 0 views
  • 30 Jul, 2021
  • 66 locations
Cohort Study of the Clinical Course of Macular Diseases in Kagawa

neovascularization (CNV), retinal vein occlusion (RVO), diabetic macular edema (DME), and so forth. The advance in vitrectomy improve visual outcomes in some maculae diseases, including epiretinal membrane (ERM

  • 0 views
  • 22 Jan, 2021
  • 1 location