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Found 30 clinical trials
Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Thyroidectomy

Hypoparathyroidism (and the resulting hypocalcemia) remains the most common morbidity after a total thyroidectomy. The identification and preservation of parathyroid glands during neck surgery has always been challenging but is crucial to avoid postoperative hypocalcemia. Recently, the specific autofluorescent characteristics of endogenous fluorophores in the parathyroid tissue have been used …

  • 0 views
  • 30 Apr, 2022
  • 1 location
Influence of the "Hypotension Probability Index" on Intraoperative and Postoperative Hypotension in ENT- and OM-Surgery

The aim of the project is to investigate whether the use of the HPI can reduce the number and duration of intra- and postoperative hypotension in ventilated patients during and two hours after extensive surgery in the head and neck area compared to the established monitoring.

  • 0 views
  • 12 Nov, 2021
  • 1 location
GDF15 Based TPF Induction Chemotherapy for OSCC Patients

The purpose of this study is to confirm the predictive value of GDF15 expression for TPF induction in T3/T4cN0M0 patients with OSCC

carcinoma of oral cavity
oral cavity cancer
induction chemotherapy
caries
cancer
  • 18 views
  • 25 Feb, 2022
  • 1 location
Phage II Trial of Stathmin as Predictive Biomarker for TPF Induction Chemotherapy in OSCC

To investigate the predictive value of stathmin expression as a predictive biomarker in OSCC patients, who treated with TPF (docetaxel, cisplatin and 5-fluorouracil ) induction chemotherapy followed by radical surgery and radiotherapy/chemoradiotherapy.

induction chemotherapy
concurrent chemotherapy
squamous cell carcinoma of the oral cavity
fluorouracil
dental caries
  • 1 views
  • 24 Feb, 2022
  • 1 location
A Phase II Trial of TPF Induction Chemotherapy in cN2 OSCC Patients

To confirm the subgroup result from TPF (docetaxel, cisplatin and 5-fluorouracil ) trial (NCT01542931) that cN2 OSCC patients could benefit from TPF induction chemotherapy compared to the standard treatment.

carcinoma of oral cavity
5-fluorouracil
oral cavity cancer
induction chemotherapy
caries
  • 0 views
  • 07 Oct, 2021
  • 1 location
Cyclin D1 Based TPF Induction Chemotherapy for Oral Squamous Cell Carcinoma Patients at Clinical N2 Stage

The purpose of this study is to To confirm the predictive value of CCND1 for TPF induction in cN2 patients with OSCC

carcinoma of oral cavity
oral cavity cancer
induction chemotherapy
caries
cancer
  • 19 views
  • 24 Feb, 2022
  • 1 location
Prognostic Significance of Lymph Node Yield and Lymph Node Ratio Prospective Observational Study

It is still unclear if Lymph Node Yield (LNY) and Lymph Node Ratio (LNR) may have a prognostic role in patients affected by carcinoma of the oral cavity and the oropharynx. Only retrospective studies are available. For this reason, this prospective, multi center, observational study should provide indications in this …

mouth cancer
carcinoma
dental caries
squamous cell carcinoma
neck dissection
  • 1 views
  • 03 Feb, 2022
  • 1 location
An Observational Study of Clinical Treatments for Patients With Oropharyngeal Carcinoma

This is a prospective, observational study evaluating the effect and efficiency of different clinical treatments for patients with oropharyngeal carcinoma (OPC). The selection of treatment for individual patient is based on tumor characteristics (tumor size and tumor location), a complete assessment of therapeutic effects (treatment effectiveness, possible dysfunction after operation, …

  • 0 views
  • 03 May, 2022
Impact of Acupuncture on Acute Dysphagia in Patients Treated With Radio-chemotherapy for Head and Neck Squamous Cell Carcinoma

This is a randomized phase 2 study on the impact of acupuncture on acute dysphagia in patients treated with radio-chemotherapy for head and neck squamous cell carcinoma

  • 0 views
  • 10 Dec, 2021
  • 2 locations
Thyroglobulin Point of Care Assay for Rapid Detection of Metastatic Differentiated Thyroid Carcinoma

Background: Despite a favorable prognosis, metastatic cervical lymph nodes (LN), are not uncommon among patients with differentiated thyroid cancer (DTC). Current guidelines recommend that a suspicious cervical LN on neck ultrasound (US) should be investigated with fine needle aspiration biopsy for cytology (FNAC) and for thyroglobulin (Tg) measurement (FNA-Tg), using …

  • 0 views
  • 01 May, 2022
  • 2 locations