Found 29 clinical trials
A Pilot Study of Radiation and Chemotherapy De-Escalation for p16-Negative Oropharyngeal Cancer and p16-Negative or Positive Laryngeal and Hypopharyngeal Cancers
The purpose of this study is to test the treatment approach of de-escalated radiation and chemotherapy followed by a planned neck dissection surgery in people with head and neck cancer. The
- 0 views
- 11 Oct, 2022
- 6 locations
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer. (NECTORS)
(neoadjuvant) chemotherapy followed by transoral surgery and neck dissection is highly effective treatment allowing competitive cure rate compared to chemo-radiotherapy with less than 10% failure rate, while
- 0 views
- 28 Apr, 2022
- 1 location
Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck
formal surgical neck dissection is performed. Given the comorbidities and risks involved in treatment of regional lymph nodes in cSCC, the role of SLNB in cSCC patients needs further clarification. This
- 0 views
- 21 Apr, 2022
- 1 location
Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma (QoLATI)
two treatment arms 1) TORS combined with neck dissection and 2) IMRT±concurrent chemotherapy with a special focus on swallowing-related QoL.
- 25 views
- 07 Oct, 2022
- 3 locations
Thermal Ablation of Cervical Metastases From Thyroid Carcinoma
This study will evaluate the clinical response and safety of ultrasound guided percutaneous thermal ablation of lymph node metastases from thyroid carcinoma as an alternative to surgical treatment. The ablation of cervical lymph node metastases from differentiated thyroid carcinoma or medullary thyroid carcinoma will be directed to lesions larger than …
- 0 views
- 07 Mar, 2021
- 1 location
TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck
This is a single-arm Phase II study of adjuvant radiation for locally advanced p16+ oropharyngeal squamous cell carcinoma. The main purpose of this research is to determine the likelihood of cancer growing back in the throat or in the neck two years after completion of radiation if lower doses of …
- 139 views
- 18 Dec, 2021
- 1 location
Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation (CAVITHY)
This prospective study evalue the inflence of pre operative vit D3 administration on post operative hypocalcemia in patients undergoing Total thyroidectomy
- 0 views
- 04 Oct, 2022
- 1 location
Intraoperative Ansa Cervicalis Nerve (ACN) Stimulation (ACS)
Recently published data suggest that stimulation of the infrahyoid strap muscles increases pharyngeal patency in patients with obstructive sleep apnea, but the innervation of these muscles by the ansa cervicalis is variable. The investigators propose a study examining the anatomic variation of the ansa cervicalis and the effect of neurostimulation …
- 0 views
- 06 Apr, 2023
- 1 location
The Optimal Neck Treatments Strategy of Early Oral Cancer Based on Adverse Pathological Factor
Cervical nodal metastasis is the most certain prognostic factor in oral cancer. Appropriate management of the neck is therefore of paramount importance in the treatment of oral cancer. However, there is still some controversy on the treatment of early maxillofacial malignancies. Currently, investigators have no accurate uniform treatment standards, including …
- 16 views
- 24 Feb, 2022
Synthetic Cartilage Implant Versus Interposition Arthroplasty in Hallux Rigidus Treatment: A Randomized Clinical Trial
A minimum of 100 patients with grade III hallux rigidus will be randomized in two parallel groups for surgical care. The first group will be submitted to the insertion of a synthetic cartilage implant at the metatarsophalangeal (MTP) joint. The second group will receive a dermal interposition arthroplasty at the …
- 0 views
- 23 Oct, 2022
- 1 location