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Found 30 clinical trials
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer. (NECTORS)

(neoadjuvant) chemotherapy followed by transoral surgery and neck dissection is highly effective treatment allowing competitive cure rate compared to chemo-radiotherapy with less than 10% failure rate, while

squamous cell carcinoma
cancer
human papillomavirus
oropharyngeal cancer
carcinoma
  • 0 views
  • 28 Apr, 2022
  • 1 location
Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma

two treatment arms 1) TORS combined with neck dissection and 2) IMRTconcurrent chemotherapy with a special focus on swallowing-related QoL.

administration intravenous
primary cancer
oropharyngeal squamous cell carcinoma
intensity-modulated radiation therapy
chemotherapy regimen
  • 25 views
  • 06 Oct, 2021
  • 3 locations
Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck

formal surgical neck dissection is performed. Given the comorbidities and risks involved in treatment of regional lymph nodes in cSCC, the role of SLNB in cSCC patients needs further clarification. This

  • 0 views
  • 21 Apr, 2022
  • 1 location
Thermal Ablation of Cervical Metastases From Thyroid Carcinoma

This study will evaluate the clinical response and safety of ultrasound guided percutaneous thermal ablation of lymph node metastases from thyroid carcinoma as an alternative to surgical treatment. The ablation of cervical lymph node metastases from differentiated thyroid carcinoma or medullary thyroid carcinoma will be directed to lesions larger than …

  • 0 views
  • 07 Mar, 2021
  • 1 location
TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck

This is a single-arm Phase II study of adjuvant radiation for locally advanced p16+ oropharyngeal squamous cell carcinoma. The main purpose of this research is to determine the likelihood of cancer growing back in the throat or in the neck two years after completion of radiation if lower doses of …

squamous cell carcinoma
oropharyngeal squamous cell carcinoma
immunohistochemistry
oropharyngeal carcinoma
cancer
  • 139 views
  • 18 Dec, 2021
  • 1 location
Validation of USPIO-enhanced MRI for Detection of Lymph Node Metastases in Head and Neck Carcinoma (USPIO-NECK)

This study evaluates the diagnostic accuracy of USPIO enhanced MRI for the detection of lymph node metastases in head-and-neck squamous cell carcinoma (SCC) using histopathology as a gold standard.

caries
squamous cell carcinoma
metastasis
squamous cell carcinoma of the oral cavity
head and neck carcinoma
  • 0 views
  • 03 Feb, 2022
  • 1 location
Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation

This prospective study evalue the inflence of pre operative vit D3 administration on post operative hypocalcemia in patients undergoing Total thyroidectomy

  • 0 views
  • 22 Aug, 2021
  • 2 locations
The Optimal Neck Treatments Strategy of Early Oral Cancer Based on Adverse Pathological Factor

Cervical nodal metastasis is the most certain prognostic factor in oral cancer. Appropriate management of the neck is therefore of paramount importance in the treatment of oral cancer. However, there is still some controversy on the treatment of early maxillofacial malignancies. Currently, investigators have no accurate uniform treatment standards, including …

metastasis
neck dissection
carcinoma
oral cancer
  • 16 views
  • 24 Feb, 2022
The Diagnostic Value of PET/MRI in Head and Neck Cancer

This study investigates the diagnostic value of PET/MRI for cervical lymph node metastases from head and neck squamous cell carcinomas.

  • 0 views
  • 23 Jan, 2021
Improved Implant for Reconstruction Purposes After Mandibular Resection (RifRam)

Study design: A single center non-randomized, prospective clinical feasibility study. Study population: Study population is composed of 10 patients ineligible for a free-flap bone reconstruction. Intervention: The selected patients will receive the newly developed, patient-specific RIfRaM mandibular implant. Objective: The aim is to provide enough evidence through model analysis, physical …

Accepts healthy volunteers
  • 0 views
  • 24 Mar, 2022
  • 1 location