Found 27 clinical trials
Trial on Intraoperative Neuromonitoring (IONM) in Thyroid Cancer Surgery. (ACTION)
>Methodology All patients undergoing total thyroidectomy with or without central compartment neck dissection, for thyroid cancers, will be eligible for participation. After
- 0 views
- 09 May, 2022
- 1 location
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer
This phase II/III trial studies how well sentinel lymph node biopsy works and compares sentinel lymph node biopsy surgery to standard neck dissection as part of the treatment for early-stage
- 12 views
- 04 Oct, 2022
- 25 locations
ESTIMation of the ABiLity of Prophylactic Central Compartment Neck Dissection to Modify Outcomes in Low-risk Differentiated Thyroid Cancer (ESTIMABL3)
+ Prophylactic Neck Dissection PND (reference group). Pre-registered patients will be randomized before surgery for tumors with class-6 cytology (Bethesda) or in the operating room after confirmation of
- 0 views
- 24 Mar, 2022
- 1 location
Study Assessing The "Best of" Radiotherapy vs the "Best of" Surgery in Patients With Oropharyngeal Carcinoma (Best Of)
cured. Treatment of early stage OPSCC can be successfully achieved with primary surgery including neck dissection, as indicated, or with definitive radiotherapy. The current standard treatment for OPSCC
- 8 views
- 04 Oct, 2022
- 29 locations
Clinical Study Evaluating the Proper Surgical Safety Margin for Early Stage Oral Tongue Cancers
A prospective multicenter randomized non-inferiority clinical trial, to evaluate the efficacy and safety of 1.0 cm-safety margin surgery, compared with 1.5 cm safety margin surgery for cT1-2N0 oral tongue cancer Summary A current standard primary treatment for oral tongue cancer is a curative surgical resection with/without adjuvant radiation treatments (or …
- 0 views
- 12 May, 2022
- 1 location
Post-operative Adjuvant Treatment for HPV-positive Tumours (PATHOS) (PATHOS)
The main objectives of the PATHOS study are: To assess whether swallowing function can be improved following transoral resection of HPV-positive OPSCC, by reducing the intensity of adjuvant treatment protocols. The aim is to personalise treatment, based on disease biology (HPV status and pathology findings), to optimise patient outcomes. To …
- 49 views
- 23 May, 2022
- 38 locations
Submandibular Gland Preservation in Neck Dissection
of the mouth. Interventions: submandibular gland is preserved during neck dissection for patients of the experimental group; submandibular gland is removed during neck dissection for patients
- 0 views
- 01 Mar, 2022
- 1 location
Definitive Chemo-Radiotherapy for Regionally Advanced Head and Neck Cancer With or Without Up-front Neck Dissection (UPFRONT-NECK)
neck dissection (ND) added to (chemo)radiotherapy ((C)RT) in terms of oncological outcome and survival. Second, with modern RT techniques, a tailored treatment followed after an up-front neck
- 15 views
- 07 Jun, 2022
- 2 locations
Peritumoral Microbubbles and CEUS for SLN Detection and Biopsy in HNSCC
is one of the most important treatment methods for head and neck squamous cell carcinoma with or without lymph node metastasis. At present, for cN0 patients, prophylactic neck dissection is
- 0 views
- 08 Jul, 2022
- 1 location
A Pilot Study of Radiation and Chemotherapy De-Escalation for p16-Negative Oropharyngeal Cancer and p16-Negative or Positive Laryngeal and Hypopharyngeal Cancers
The purpose of this study is to test the treatment approach of de-escalated radiation and chemotherapy followed by a planned neck dissection surgery in people with head and neck cancer. The
- 0 views
- 11 Oct, 2022
- 6 locations