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Found 117 clinical trials
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Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

: HFPEF patients in the Swedish Heart Failure Registry (2550 patients) and HFPEF patients in US (650 patients). HFPEF defined as symptoms/signs of HF, elevated NTproBNP (B-type Natriuretic Peptide; N

aldosterone
nt-probnp
natriuretic peptide
b-type natriuretic peptide
spironolactone
  • 57 views
  • 02 Jul, 2021
  • 148 locations
None
BNP Testing in Patients With SOB on Presentation to ED

A trial to examine whether a new heart failure blood test can improve the outcome of patients presenting to the Emergency Department with shortness of breath. We hypothesise that a BNP test performed in real-time in patients presenting to the Emergency Department with shortness of breath will help identify additional …

dyspnea
  • 43 views
  • 07 Nov, 2020
  • 1 location
None
ARNI in Asymptomatic Patients With Elevated Natriuretic Peptide and Elevated Left Atrial Volume Index eLEvation

diabetes or other risk factors for developing heart failure (elevated levels of natriuretic peptide and elevated left atrial volume index). Patients will be randomized to receive LCZ696 or valsartan (and

valsartan
natriuretic peptide
sacubitril
diabetes
hypertension
  • 0 views
  • 08 Nov, 2020
  • 1 location
None
A Study to Assess the Safety Tolerability and Efficacy of IONIS-AGT-LRx in Participants With Chronic Heart Failure With Reduced Ejection Fraction

to evaluate the effect of IONIS-AGT-LRx weekly SC injection on plasma AGT concentration and N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) levels at each scheduled visit in chronic

  • 0 views
  • 25 Nov, 2021
  • 16 locations
None
Acute Heart Failure - COngestion Discharge Evaluation

decongestion at the end of hospitalisation for AHF assessed by a standardised clinical score, a natriuretic peptide dosage or by cardiac and pulmonary ultrasound . Adapting treatment according to lung

natriuretic peptide
congestion
pulmonary congestion
  • 0 views
  • 24 Sep, 2021
  • 1 location
None
Right Ventricular Apical Versus True Mid-septal Pacing

concentration of N-terminal pro brain natriuretic peptide (NT-proBNP) from baseline to 6 months, 1 year and three years. Secondary end-points are changes in echo-parameters of LV synchrony. Discussion

  • 0 views
  • 22 Jun, 2021
  • 1 location
None
Comparison of Once Daily 40 mg Torsemide With Twice-daily 40 mg Furosemide

To compare the effects of 40 mg once-daily Torsemide ER to 40 mg twice daily Furosemide on 24-hour sodium excretion.

  • 5 views
  • 23 Jan, 2021
  • 1 location
None
Effect Levosimendan Administration on Postoperative NT-proBNP in Cardiac Risk Patients

This is a prospective randomised trial investigating the effect of a preemptive administration of levosimendan on postoperative cardiac NT-proBNP concentrations.

  • 0 views
  • 29 Jan, 2021
  • 1 location
None
An Open-Label Study of Apabetalone in Covid Infection

The primary objective of the study is to evaluate the safety and effect on clinical course of oral apabetalone in hospitalized subjects with Covid-19 infection

  • 0 views
  • 09 Nov, 2021
  • 1 location
None
A Comparison of Hydrochlorothiazide and Metolazone in Combination With Furosemide in Congestive Heart Failure Patients

The purpose of this research study is to compare the effectiveness of hydrochlorothiazide or metolazone in combination with furosemide. Patients with heart failure suffer from swelling because of too much fluid in the body. Furosemide, hydrochlorothiazide, and metolazone are all water pills used to treat the swelling. For most patients, …

diuretics
furosemide
edema
ejection fraction
congestive heart failure
  • 8 views
  • 07 Nov, 2020
  • 1 location