Found 44 clinical trials
Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)
dupilumab to reduce nasal polyp formation in participants with AFRS To evaluate the efficacy of dupilumab in improving overall symptom severity and quality of life in AFRS To evaluate
- 123 views
- 19 May, 2023
- 5 locations
EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 Patients (EVEREST)
Primary Objective -To evaluate the efficacy of dupilumab compared to omalizumab in reducing the polyp size and improving sense of smell Secondary Objectives To evaluate the efficacy of dupilumab in improving CRSwNP symptoms at Week 24 compared to omalizumab To evaluate the efficacy of dupilumab in improving lung function at …
- 92 views
- 12 May, 2023
- 76 locations
Dupilumab in CRSsNP (Liberty CRSsNP)
Primary Objective: To evaluate the efficacy of dupilumab as assessed by the reduction at Week 24 in sinus opacification on computerized tomography (CT) scan in the dupilumab group only Secondary Objectives: To evaluate the efficacy of dupilumab as assessed by the reduction at Week 24 in sinus opacification on CT …
- 49 views
- 12 May, 2023
- 8 locations
Nasal Polyps w/CRS
The aim of the present study is to investigate the efficacy and safety of Tezepelumab in participants with severe chronic rhinosinusitis with nasal polyps (CRSwNP).
- 0 views
- 29 Sep, 2022
- 1 location
ENLIGHTEN 1: A Phase III, Randomized, Blinded, Controlled, Parallel-Group Trial to Evaluate the Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis (CRS) in adults
Evaluates the safety and efficacy of the LYR-210 matrix in patients with chronic rhinosinusitis without nasal polyps
- 2 views
- 07 Mar, 2022
- 1 location
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate CBP-201 in Adult Patients with Chronic Rhinosinusitis with Nasal Polyps
To evaluate the efficacy of CBP-201 in patients with chronic rhinosinusitis with nasal polyps
- 15 views
- 07 Mar, 2022
- 1 location
A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal Polyposis
A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal
- 0 views
- 17 Feb, 2022
- 1 location
Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis (WAYPOINT)
A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal
- 55 views
- 04 Oct, 2022
- 87 locations
Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)
AFRS To evaluate the efficacy of dupilumab to reduce nasal polyp formation in patients with AFRS To evaluate the efficacy of dupilumab in improving overall symptom
- 8 views
- 10 Apr, 2023
- 31 locations
Effect of Benralizumab in Patients With Severe Nasal Polyps
This is a randomized placebo controlled trial to evaluate the effect of benralizumab on people with severe nasal polyps.
- 3 views
- 08 Nov, 2020
- 1 location