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Found 58 clinical trials
Featured trial
ENLIGHTEN 1: A Phase III, Randomized, Blinded, Controlled, Parallel-Group Trial to Evaluate the Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis (CRS) in adults

Evaluates the safety and efficacy of the LYR-210 matrix in patients with chronic rhinosinusitis without nasal polyps

nasal polyps
rhinosinusitis
  • 0 views
  • 07 Mar, 2022
  • 1 location
Featured trial
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate CBP-201 in Adult Patients with Chronic Rhinosinusitis with Nasal Polyps

To evaluate the efficacy of CBP-201 in patients with chronic rhinosinusitis with nasal polyps 

nasal polyps
rhinosinusitis
  • 0 views
  • 07 Mar, 2022
  • 1 location
Featured trial
A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal Polyposis

A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal

  • 0 views
  • 17 Feb, 2022
  • 1 location
Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis (WAYPOINT)

A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal

  • 55 views
  • 14 May, 2022
  • 84 locations
Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)

AFRS To evaluate the efficacy of dupilumab to reduce nasal polyp formation in patients with AFRS To evaluate the efficacy of dupilumab in improving overall symptom

  • 8 views
  • 16 May, 2022
  • 36 locations
Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)

AFRS To evaluate the efficacy of dupilumab to reduce nasal polyp formation in patients with AFRS To evaluate the efficacy of dupilumab in improving overall symptom

  • 9 views
  • 27 May, 2022
  • 38 locations
Effect of Benralizumab in Patients With Severe Nasal Polyps

This is a randomized placebo controlled trial to evaluate the effect of benralizumab on people with severe nasal polyps.

  • 3 views
  • 08 Nov, 2020
  • 1 location
Dupilumab Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis

The investigators will investigate the efficacy of dupilumab in patients with severe eosinophilic CRSsNP who are resistant to the conventional treatment with intranasal corticosteroids and have significantly extensive disease involving more than 2 sinuses bilaterally in sinus CT scan and Lund-Mackay sinus (LMK) CT score >=10 at baseline.

  • 2 views
  • 16 Aug, 2021
  • 1 location
The Study of CM310 in Patients With Chronic Rhinosinusitis With Nasal Polyps

This is an open-label, single-arm, multicenter, extension study to evaluate the long-term safety and efficacy of CM310 in patients with CRSwNP.

  • 0 views
  • 19 Dec, 2021
  • 1 location
Dupilumab in Japanese Patients With Chronic Rhinosinusitis With Nasal Polyp (SINUS-M52)

This is a Phase 4, open-label, single-arm, multicenter study to evaluate the efficacy and safety of dupilumab subcutaneous (SC) injection monotherapy in Japanese participants aged 18 or older with CRSwNP that is not adequately controlled with existing therapies. Duration of study period (per participant): Screening Period (2 to 4 weeks) …

  • 0 views
  • 13 May, 2022
  • 1 location