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Found 11 clinical trials
A Randomized, Double-Blind, Single-Dose, Parallel, Placebo-Controlled Pivotal Trial to Confirm the Efficacy of a Fixed Dose Combination Tablet of Naproxen Sodium and Caffeine to Effectively Alleviate Postsurgical Dental Pain

subsequently have moderate to severe tooth pain. The study treatment naproxen sodium suppresses inflammatory pain by reducing inflammation. In the US, naproxen has been marketed since 1976, and

Accepts healthy volunteers
  • 0 views
  • 24 Oct, 2022
  • 1 location
NSAIDs in Sciatica NSAIDS IN SCIATICA (NIS)

This study will evaluate whether treatment with Naproxen 500 mg twice daily is superior to placebo for the improvement of leg pain in patients with sciatica. Half of patients will receive

radiating pain
paresthesia
NSAID
numbness
weakness
  • 504 views
  • 13 May, 2022
  • 4 locations
Inflammation and Daily Life Study

for four weeks, participants will take either an anti-inflammatory medication (naproxen) twice daily, or a placebo pill twice daily. Participants will also answer daily questions during the 2-week

Accepts healthy volunteers
  • 0 views
  • 05 Jun, 2022
  • 1 location
Novel Non-opioid Post-surgical Pain Treatment in Females

This study aims to determine if treatment with Carbidopa/Levodopa and Naproxen in females (biological sex) with acute pain after a bunionectomy or toe fusion (24hrs, 48hrs and 5 days) will

naproxen
opioid
bunionectomy
acute pain
  • 0 views
  • 27 Nov, 2021
  • 1 location
Mechanistic Characterization of Uterine Pain (MCUP)

oxygenation, 3) a combination of phenotypes 1 & 2, and 4) a non-uterine source. Aim #2: Evaluate the effects of naproxen on myometrial activity, perfusion, and/or oxygenation with respect to pain

uterine pain
pelvic mri
naproxen
adenomyosis
primary dysmenorrhea
  • 148 views
  • 17 Jun, 2022
  • 1 location
Opioid Therapy vs Multimodal Analgesia in Head and Neck Cancer

: pregabalin, naproxen, and acetaminophen, with the ability to switch over to opioid medications if needed. In addition to pain level scores, this study will compare opioid use (length of time and doses taken

opioid
chemoradiotherapy
  • 98 views
  • 10 Sep, 2021
  • 1 location
RCT of IV Dexamethasone to Prevent Relapse in the Treatment of Migraine in a Paediatric ED

regimen or if they did not respond to the initial abortive migraine therapy. All included patients were discharged on a 48-hour course of naproxen and with a headache diary to fill out and return. The

naproxen
prochlorperazine
metoclopramide
headache
Accepts healthy volunteers
  • 18 views
  • 11 May, 2022
  • 1 location
Accessible Acupuncture for the Warrior With Acute Low Back Pain

The objective of this study is to determine if auricular acupuncture and/or the acupuncture point governor vessel 26 (GV26) with manual tonification is superior to conservative management (NSAIDs) at reducing acute low back pain (less than 4 weeks in duration).

conservative management
naproxen
acute back pain
low back pain
NSAID
  • 104 views
  • 30 Apr, 2022
  • 1 location
Premedication With Intranasal Dexmedetomidine in Sedation of Patients Undergoing Total Knee Arthroplasty (TKADEX)

This study aims to find out if preoperatively given dexmedetomidine is effective analgesic adjuvant for treating postoperative pain in patients undergoing elective total knee arthroplasty (TKA). Another aim is to determine if premedication with intranasal dexmedetomidine could provide sufficient sedation to alleviate anxiety during TKA.

  • 0 views
  • 28 Oct, 2022
  • 1 location
Eliminating Narcotic Prescriptions From Outpatient Minimally Invasive Gynecologic Surgery (eNARCOS)

Laparoscopic gynecologic surgeries are generally very well tolerated procedures, and patients are able to go home on the same day, with a prescription for pain control. There is currently a very wide range of prescription practice within the gynecology community in regards to opioids following surgery, and patients are going …

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location