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Found 33 clinical trials
N-Acetylcysteine for Youth Cannabis Use Disorder

This is a 12-week randomized, placebo-controlled trial of N-acetylcysteine for cannabis use disorder (CUD) in youth (N=192). Participants will be randomized to double-blind NAC or PBO, yielding

  • 26 views
  • 19 Aug, 2022
  • 1 location
Intratympanic N-Acetylcysteine for Prevention of Cisplatin-induced Ototoxicity.

Although many intratympanic agents have been attempted, N-Acetylcysteine (NAC) appears to be the most promising and is a powerful, commonly used anti-oxidant. The goal of this prospective phase

  • 3 views
  • 28 Feb, 2022
  • 1 location
Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)

of N-acetylcysteine (NAC) after an intra-articular knee fracture and its effect on the cartilage cell viability. Their study demonstrated that chondrocyte cell viability after an injection of NAC

  • 1 views
  • 22 Aug, 2021
  • 1 location
Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19

amino-acids glycine and cysteine (provided as N-acetylcysteine) improves GSH deficiency and mitochondrial function, and lowers oxidative stress, inflammation, and endothelial dysfunction. The

  • 1 views
  • 25 Mar, 2022
  • 1 location
N-Acetylcysteine Protection Against Radiation Induced Cellular Damage

different response to IR results from inherited variants in genes involved in DNA damage repair. N-acetylcysteine (NAC) is an aminoacid that can directly neutralize free radicals and increase antioxidant

  • 0 views
  • 15 Feb, 2021
  • 1 location
N-Acetylcysteine for Adolescent Alcohol Use Disorder

This is a 8-week randomized, placebo-controlled trial testing the effects of N-acetylcysteine (NAC), on a platform of weekly evidence-based brief alcohol intervention for 120 adolescents with

n-acetylcysteine
  • 1 views
  • 28 Feb, 2022
  • 1 location
Treatment of Systemic Lupus Erythematosus (SLE) With N-acetylcysteine (NAC)

Systemic lupus erythematosus (SLE) is a chronic inflammatory disease which often has debilitating and potentially life-threatening consequences. The cause of SLE is unknown and current therapies lack specificity and carry significant side-effects. We previously discovered the depletion of glutathione in lymphocytes of patients with SLE and associated this metabolic change …

methotrexate
lupus
azathioprine
corticosteroids
prednisone
  • 0 views
  • 28 Jun, 2022
  • 1 location
N-ACetylcysteine to Reduce Infection and Mortality for Alcoholic Hepatitis

mortality in patients treated with N-acetylcysteine combined with prednisolone when compared to prednisolone alone. The current study seeks to reveal whether the mechanism by which NAC reduces

prednisolone
serum bilirubin level
n acetylcysteine
n-acetylcysteine
  • 1 views
  • 16 Nov, 2021
  • 1 location
N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms

This study investigates the effects of repeated NAC administration on glutamate concentrations in the anterior cingulate cortex (ACC), on neurocognitive functioning, and on neuro-inflammatory parameters in adult cannabis-dependent individuals.

n-acetylcysteine
Accepts healthy volunteers
  • 15 views
  • 23 Feb, 2022
  • 1 location
Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1 (DoDNAC)

complication. In this project, the investigators will assess the safety and clinical benefit of N-acetylcysteine (NAC) as a pharmacological intervention in children with NF1. This drug choice is based on the

Accepts healthy volunteers
  • 2 views
  • 11 Mar, 2022
  • 1 location