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Found 64 clinical trials
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Environmental Risk Factors for the Anti-synthetase Syndrome

autoimmune disorder myositis weakens the muscles and may cause other health problems. Environmental exposures associated with myositis include ultraviolet radiation, stressful life events and muscle

pulmonary function test
myositis
autoimmune disease
house dust
pulmonary disease
  • 142 views
  • 12 Sep, 2021
  • 5 locations
None
Real Life Study on Iron Isomaltoside 1000 in the Treatment of ID in CKD Heart Failure ObGyn IBD Cancer and Elective Surgery (Real-CHOICE).

general and IIM (iron isomaltoside 1000) treatment particularly before and after IIM treatment in iron deficient patients with or without anemia in the real-world clinical setting after commercial

cancer
monofer
heart failure
iron isomaltoside 1000
iron therapy
  • 0 views
  • 01 Apr, 2021
  • 14 locations
None
Clinical Responsiveness of Dermatomyositis Using Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI)

The Evaluation of Clinical Responsiveness Using the Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI), established in 2008, is a one-site database study conducted at the University of Pennsylvania. The database has yielded valuable information and clinical insights into the pathophysiology, disease processes, including psychological responses, treatments and quality of …

dermatomyositis
  • 1 views
  • 24 Jan, 2021
  • 1 location
None
Musculoskeletal Nociceptive Pain in Participants With Neuromuscular Disorders

, including patients with the following neuromuscular disorders: histologically confirmed inclusion body myositis (IBM), genetically confirmed late-onset Pompe disease (LOPD), genetically confirmed spinal

dyspnea
exercise tests
  • 0 views
  • 18 Jun, 2021
  • 1 location
None
Prospective Registry of Corona Virus Disease 2019 (Covid-19) Patients With Neuromuscular Involvement

Prospective registry for multimodal assessment of neuromuscular pathology associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, enrolling consecutive patients with corona virus disease 2019 (Covid-19), who are admitted to the intensive care unit of the department of anesthesiology and intensive care medicine, or the department of neurology at …

infection laboratory
SARS
creatine kinase
covid-19
coronavirus infection
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Muscle Weakness in COVID-19 Patients

), but also to the direct action of virus (SARS-Cov-2 myositis). The general purpose of the research is to quantify the spread of symptoms and signs of muscle weakness and pain among the patient

  • 0 views
  • 19 Jul, 2021
  • 1 location
None
Evaluation of Hand Functions in Newly Diagnosed Primary Sj gren's Syndrome

joint involvement of PSS is usually moderate (<5 affected joints) and mostly affects the small joints of the hands and upper extremities. PSS may also be responsible for myositis. Widespread pain

rheumatic diseases
Accepts healthy volunteers
stiffness
arthralgia
autoimmune disease
  • 0 views
  • 18 Nov, 2021
  • 1 location
None
ILD-SARDs Registry and Biorepository

A complex interaction between demographic, environmental and genetic mechanisms impact the onset, severity and outcome of ILD-SARDs through dysregulation of the immune system and lung pro-biotic pathways. Comorbidity and genetic risk indicate that there are overlapping pathogenic mechanisms among SARDs, some of which underlie ILD in different SARDs. The purpose …

chest ct
bronchoalveolar lavage
connective tissue disease
lung disease
  • 0 views
  • 18 Sep, 2021
  • 1 location
None
An Exploratory Study on the Efficacy and Safety of Abatacept in the Treatment of Refractory Dermatomyositis

Dermatomyositis is a heterogeneous disease characterized by involvement of the proximal muscles of the extremities. Some patients have treatment failure or intolerance to the above treatment regimens, which is called refractory dermatomyositis. Abatacept has been approved by the FDA for the treatment of three types of rheumatoid immune diseases, and …

cyclophosphamide
methotrexate
abatacept
cyclosporine
glucocorticoids
  • 0 views
  • 09 Jul, 2021
  • 1 location
None
Ravulizumab Versus Placebo in Adult Participants With Dermatomyositis

This is a Phase 2/3, double-blind, randomized, placebo-controlled, parallel group, multicenter study to evaluate the efficacy, safety, pharmacokinetics, pharmacodynamics, and immunogenicity of ravulizumab in adult participants with dermatomyositis (DM).

corticosteroids
methotrexate
dermatomyositis
azathioprine
rituximab
  • 2 views
  • 16 Nov, 2021
  • 1 location