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Found 64 clinical trials
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Pregnancy and Medically Assisted Conception in Rare Diseases

' pregnancies. Using a single computer server, the investigators plan to set up a large prospective study of pregnancies in patients with rare diseases: various forms of myositis, lupus, antiphospholipid

myositis
beta-hcg
connective tissue diseases
sjogren's syndrome
connective tissue disorder
  • 239 views
  • 13 May, 2021
  • 2 locations
None
Clinical Research on Advanced Warning Factors Of Respiratory Injury in Dermatomyositis

Dermatomyositis (DM) is a highly heterogeneous autoimmune disease characterized by rash and myasthenia. Beside these, respiratory involvement is one of the common complications of DM. Interstitial lung disease (ILD) occur in approximately 90% of patients with DM, part of them may manifest rapidly progressive-interstitial lung disease (rp-ILD), which progresses into …

dermatomyositis
rash
autoimmune disease
  • 0 views
  • 09 Jul, 2021
  • 1 location
None
Studies of the Natural History Pathogenesis and Outcome of Autoinflammatory Diseases Including Juvenile Dermatomyositis

Purpose The purpose of this protocol is 1. To comprehensively evaluate patients with autoinflammatory diseases clinically, genetically and immunologically at the autoinflammatory disease clinic at the NIH. 2. To follow patients with autoinflammatory Diseases that are genetically defined including Neonatal-Onset Multisystem Inflammatory Disease (NOMID), the most severe clinical phenotype of …

computerized tomography
x-rays
skin inflammation
il-1
deficiency
  • 497 views
  • 08 Nov, 2021
  • 1 location
None
Rheumatology Patient Registry and Biorepository

To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.

connective tissue disease
polymyositis
rheumatism
autoimmune disease
giant cell arteritis
  • 513 views
  • 14 Oct, 2021
  • 1 location
None
Phenomics in Autoimmune and Inflammatory Diseases

The family of inflammatory/autoimmune systemic diseases (IAD) form a continuum from pure inflammatory diseases to pure autoimmune diseases, encompassing a large panel of inflammatory diseases with some autoimmune components, and vice versa. Cross phenotyping of patients with IAD should be heuristic and help revise the nosography and the understanding of …

colitis
autoimmune disease
tumour necrosis
ulceration
autoimmune diseases
  • 333 views
  • 24 Jan, 2021
  • 3 locations
None
At-Home Research Study for Patients With Autoimmune Inflammatory Genetic Hematological Infectious Neurological CNS Oncological Respiratory Metabolic Conditions

We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research. We make it easy for patients to contribute to research for medical conditions that matter most to them, regardless of their location or ability to travel.

Accepts healthy volunteers
  • 88 views
  • 01 Dec, 2021
  • 1 location
None
Evaluation of Patients With HAM/TSP

Objective Human T-lymphotropic virus type-I-associated myelopathy / tropical spastic paraparesis (HAM/TSP) is a rare neurologic disorder that affects less than 5% of patients infected with the HTLV-I virus. The purpose of this protocol is to study the natural history of HAM/TSP by monitoring clinical progression of patients longitudinally. Additionally, we …

Accepts healthy volunteers
  • 20 views
  • 18 Nov, 2021
  • 1 location
None
DNA Diagnostic System for Statin Safety and Efficacy

Lipitor®, Zocor®, and Crestor® are statin drugs commonly taken to lower cholesterol and prevent heart disease. Statins lower cholesterol by different amounts in different patients and sometimes statins cause muscle pain, cramps, or weakness. This study will examine genetic differences in the blood of patients taking statins to predict both …

statin
lipitor
heart disease
hmg-coa reductase inhibitors
simvastatin
  • 27 views
  • 07 Nov, 2020
  • 2 locations
None
Optimizing Treatment on Idiopathic Inflammatory Myopathies

As a T2T, our patients with idiopathic inflammatory myopathies will receive pulse therapies with methyprednisolone and/or human intravenous immunoglobulin, or only methyprednisolone at disease

myositis
igiv
  • 27 views
  • 27 Jan, 2021
  • 1 location
None
Sporadic Inclusion Body Myositis Natural History Study

This is a prospective natural history study on patients with clinically defined sIBM. Participants will be assessed every 6 months over two years (five visits total). We will include 150 participants, enrolled across 13 sites, with sporadic IBM, diagnosed according to established criteria.

inclusion body myositis
  • 0 views
  • 03 Dec, 2021
  • 13 locations