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Found 67 clinical trials
Role of Metformin on Muscle Health of Older Adults

Muscle atrophy and insulin resistance are common after bed rest in healthy older adults. Metformin treatment has been shown to improve insulin sensitivity and attenuate muscle loss in insulin resistance adults though the mechanisms are not fully known. Metformin used as a preventive strategy to maintain muscle and metabolic health …

Accepts healthy volunteers
bed rest
insulin
  • 1 views
  • 07 Jul, 2022
  • 1 location
Leflunomide for Musculoskeletal GVHD After Allogeneic Stem Cell Transplant

Graft versus host disease (GVHD) is a well-known complication of allogeneic transplant. In GVHD, the cells of the donor attack the patient's tissues and cause damage. It can affect any organ or system of the body. In a proportion of patients, it affects the joints and muscles. This is known …

  • 0 views
  • 28 Jun, 2021
  • 1 location
Resistance Training Intervention to Improve Physical Function in Patients With Pancreatic Cancer Receiving Combination Chemotherapy or Have Undergone Surgery PancStrength Study

This clinical trial studies the safety of a real-time tele-exercise resistance training (training done using a tablet) in maintaining skeletal muscle, strength, physical function, and health-related quality of life in patients with pancreatic cancer who are receiving combination chemotherapy or have undergone surgery for the treatment of pancreatic cancer. Tele-exercise …

  • 0 views
  • 17 Apr, 2021
  • 1 location
COvid-19 Vaccine Booster in Immunocompromised Rheumatic Diseases (COVBIRD)

People living with Systemic autoimmune rheumatic diseases (SARDs) face a new and urgent dilemma: immunosuppression increases risk for worse COVID-19 infection, yet an immune stimulation, such as vaccination, could re-activate their disease. Fear of vaccine-related disease reactivation is not of concern in other immunosuppressed groups (e.g. patients receiving chemotherapy or …

myositis
lupus
rheumatic diseases
progressive systemic sclerosis
arthritis
  • 6 views
  • 08 Aug, 2022
  • 1 location
The Fibrodysplasia Ossificans Progressiva (FOP) Connection Registry

The Fibrodysplasia Ossificans Progressiva (FOP) Connection Registry is a global, non-interventional, voluntary database that captures demographic and disease data directly from FOP patients and their caregivers via a secure, web-based patient portal. A physician portal (in development) will allow physicians to enter clinical data about their patients. The objectives are …

  • 44 views
  • 21 Jan, 2021
  • 1 location
Adult and Juvenile Myositis

inflammatory muscle disease that can damage muscles and other organs, resulting in significant disability. Children or adults with polymyositis or dermatomyositis or a related condition may be

autoimmune disease
skin inflammation
vision loss
nonsteroidal anti-inflammatory drugs (nsaids)
Accepts healthy volunteers
  • 166 views
  • 10 Aug, 2022
  • 4 locations
Clinical Database and Biobank of Patients With Inflammatory Myopathies: the MASC Project (Myositis DNA Serum Cells) (MASC)

Myositis are rare diseases for which the development of a cohort associated with a bank of biological samples (biobank) will allow for the conduct of researches to better delineate the

myopathy
rare diseases
polymyositis
MRI
dermatomyositis
  • 0 views
  • 09 Sep, 2021
  • 2 locations
Study and Treatment of Inflammatory Muscle Diseases

This study of inflammatory muscle diseases-polymyositis and dermatomyositis and related disorders-will examine what causes these diseases and describe the clinical features (signs and symptoms

autoimmune disease
Accepts healthy volunteers
dermatomyositis
white blood cells
biopsy incision
  • 844 views
  • 25 Jul, 2022
  • 1 location
Investigating Genes in Patients With Polymyositis and Dermatomyositis

Polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM)belong to a group of inflammatory muscle disorders, of unknown cause, that are characterised by skeletal muscle

skeletal muscle enzymes
myositis
lupus
dermatomyositis
arthritis
  • 105 views
  • 29 Sep, 2021
  • 1 location
Clinico-biological Collection to Investigate the Physiopathology of Systemic Autoimmune Diseases (EMA)

The aim of this project is to start a biological and clinical collection of patients presenting systemic autoimmune disease. This collection will provide appropriate biological samples to identify new biomarkers and to be accessible to the medical, scientific and industrial communities for the identification of new therapeutic strategies

autoimmune disease
myositis
lupus
scleroderma
  • 0 views
  • 08 Jun, 2022
  • 1 location