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Found 22 clinical trials
Early Left Atrial Septostomy Versus Conventional Approach After Venoarterial Extracorporeal Membrane Oxygenation

The use of venoarterial-extracorporeal membrane oxygenation(VA-ECMO) was associated with lower in-hospital mortality in patients with cardiogenic shock. However, VA-ECMO has a deleterious effect for hemodynamics. It can increase left ventricular end-diastolic pressure(LVEDP), followed by left ventricular dilatation, abnormal opening of aortic valve and jeopardizes of myocardial recovery. Therefore, several methods …

  • 0 views
  • 30 Apr, 2021
  • 1 location
HYdrocortisone and VAsopressin in Post-RESuscitation Syndrome

The primary objective is to demonstrate the superiority of arginine-vasopressin (AVP) and hydrocortisone compared with norepinephrine regarding day-30 survival and neurological recovery in post-cardiac arrest patients with hemodynamic failure.

  • 0 views
  • 23 Jun, 2021
  • 1 location
Percutaneous Revascularization in Infarction With Late Presentation and Absence of Viability: Effects on Left Ventricular Remodeling and Contractility

The purpose of this study is to evaluate whether late recanalization in patients with ST elevation myocardial infarction (STEMI) without Viability on Cardiovascular Magnetic Resonance Image (MRI) can reduce the reverse remodeling through the reduction of the End Systolic Volume (ESV) at 6 months.

  • 0 views
  • 21 Jan, 2022
  • 1 location
Effects of Treatment With Biological Agents on Vascular and Cardiac Function in Psoriasis

myocardial dysfunction are impaired in patients with psoriasis compared to normal controls ,coronary artery disease patients and untreated hypertension subjects. The investigators also examined the effect of

apremilast
atherosclerosis
Accepts healthy volunteers
cyclosporine
ustekinumab
  • 0 views
  • 21 Nov, 2021
  • 1 location
Milrinone Versus Placebo in Patients With Septic Shock

refractory shock and multi-organ failure. Myocardial dysfunction is a relatively common complication of septic shock. This causes a decrease in the amount of cardiac output, resulting in insufficient blood

  • 0 views
  • 27 Nov, 2021
  • 2 locations
Molecular Imaging of Primary Amyloid Cardiomyopathy

Cardiac amyloidosis is a major cause of early treatment-related death and poor overall survival in individuals with systemic light chain amyloidosis. This project will develop a novel approach to visualize cardiac amyloid deposits using advanced imaging methods. The long-term goal of this work is to identify the mechanisms of cardiac …

MRI
florbetapir
nesiritide
amyloid deposits
heart failure
  • 28 views
  • 30 Sep, 2021
  • 1 location
Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest

Comatose patients resuscitated from Out-of-Hospital Cardiac Arrest (OHCA) often develop a complicated systemic inflammatory response and have a poor prognosis with neurological damage being the most common cause of death. This study will investigate the anti-inflammatory and neuroprotective effect of early treatment with the glucocorticoid methylprednisolone measured by interleukin-6 and …

  • 0 views
  • 26 Jan, 2021
  • 2 locations
Cardiac FDG PET Viability Registry (CADRE)

Positron Emission Tomography (PET) is a non-invasive, unique nuclear imaging technique that allows the evaluation of blood flow in the heart and provides information about the cell activity of specific organs such as the heart and brain. It also provides useful information for the management of patients with poor pumping …

cancer
left ventricular dysfunction
arterial disease
heart failure
positron emission tomography
  • 88 views
  • 23 Jan, 2022
  • 4 locations
Multicenter Prospective Study of Low-Flow Low-Gradient Aortic Stenosis (TOPAS Study)

assess the severity of valvular and myocardial dysfunction in patients with LF-LG AS are far from being optimal, and as a consequence, quantification of disease severity and therapeutic management may

MRI
ct scan
stenosis
heart disease
valvular disease
  • 84 views
  • 26 Sep, 2021
  • 11 locations
High-Sensitivity Troponin T Plasma Levels in Patients With Aortic Stenosis (Tyrolean Aortic Stenosis Study-2)

TASS-2 (Tyrolean Aortic Stenosis Study-2) aims to characterize the clinical value of minimally elevated troponin T plasma levels both in patients with asymptomatic and symtomatic aortic stenosis.

stenosis
troponin
  • 120 views
  • 31 Oct, 2021
  • 1 location