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Found 29 clinical trials
Early Left Atrial Septostomy Versus Conventional Approach After Venoarterial Extracorporeal Membrane Oxygenation (EARLY-UNLOAD)

The use of venoarterial-extracorporeal membrane oxygenation(VA-ECMO) was associated with lower in-hospital mortality in patients with cardiogenic shock. However, VA-ECMO has a deleterious effect for hemodynamics. It can increase left ventricular end-diastolic pressure(LVEDP), followed by left ventricular dilatation, abnormal opening of aortic valve and jeopardizes of myocardial recovery. Therefore, several methods …

  • 0 views
  • 10 Aug, 2022
  • 1 location
HYdrocortisone and VAsopressin in Post-RESuscitation Syndrome

The primary objective is to demonstrate the superiority of arginine-vasopressin (AVP) and hydrocortisone compared with norepinephrine regarding day-30 survival and neurological recovery in post-cardiac arrest patients with hemodynamic failure.

  • 0 views
  • 23 Jun, 2021
  • 1 location
Percutaneous Revascularization in Infarction With Late Presentation and Absence of Viability: Effects on Left Ventricular Remodeling and Contractility

The purpose of this study is to evaluate whether late recanalization in patients with ST elevation myocardial infarction (STEMI) without Viability on Cardiovascular Magnetic Resonance Image (MRI) can reduce the reverse remodeling through the reduction of the End Systolic Volume (ESV) at 6 months.

  • 0 views
  • 26 Mar, 2022
  • 1 location
Effects of Treatment With Biological Agents on Vascular and Cardiac Function in Psoriasis

myocardial dysfunction are impaired in patients with psoriasis compared to normal controls ,coronary artery disease patients and untreated hypertension subjects. The investigators also examined the effect of

atherosclerosis
etanercept
cyclosporine
Accepts healthy volunteers
apremilast
  • 0 views
  • 18 Apr, 2022
  • 1 location
Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/Valsartan (TREAT-HF)

To determine feasibility of recruitment and tolerability of treatment with sacubitril-valsartan among adult age survivors of cancer diagnosed at or before age 39 who have stage B heart failure.

dyspnea
cardiac mri
valsartan
heart failure
cancer
  • 0 views
  • 23 May, 2022
  • 1 location
Milrinone Versus Placebo in Patients With Septic Shock

refractory shock and multi-organ failure. Myocardial dysfunction is a relatively common complication of septic shock. This causes a decrease in the amount of cardiac output, resulting in insufficient blood

  • 0 views
  • 27 Nov, 2021
  • 2 locations
The Efficacy of Adjunctive Use of Ondansetron in Patients With Sepsis and Septic Shock

demonstrated that adverse outcomes in sepsis patients are closely related to the development of myocardial dysfunction 3 . The mortality of sepsis combined with cardiac functional insufficiency has increased

inflammatory response
septic shock
severe sepsis
immunostimulants
shock
  • 0 views
  • 15 Jun, 2022
  • 1 location
Myocardial Function and Vitamin D Supplementation in Diabetes. (VitaDD)

Vitamin D deficiency is recognized as a cardiovascular risk factor. Diabetic patients are of major risk for cardiovascular diseases and typically present with Vitamin D deficiencies. Myocardial function is altered in both type I and II diabetic patients but no data is today available on the effect of Vitamin D …

vitamin d supplementation
diabetes
vitamins
vitamin d
cholecalciferol
  • 13 views
  • 25 Mar, 2022
  • 1 location
Molecular Imaging of Primary Amyloid Cardiomyopathy (MICA)

Cardiac amyloidosis is a major cause of early treatment-related death and poor overall survival in individuals with systemic light chain amyloidosis. This project will develop a novel approach to visualize cardiac amyloid deposits using advanced imaging methods. The long-term goal of this work is to identify the mechanisms of cardiac …

b-type natriuretic peptide
multiple myeloma
remission
nt-probnp
cardiomyopathy
  • 28 views
  • 23 Feb, 2022
  • 1 location
Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest (STEROHCA)

Comatose patients resuscitated from Out-of-Hospital Cardiac Arrest (OHCA) often develop a complicated systemic inflammatory response and have a poor prognosis with neurological damage being the most common cause of death. This study will investigate the anti-inflammatory and neuroprotective effect of early treatment with the glucocorticoid methylprednisolone measured by interleukin-6 and …

inflammatory response
interleukin-6
  • 0 views
  • 10 Mar, 2022
  • 2 locations