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Found 759 clinical trials
Featured trial
The Axcelsius Study: A Study of ONO-7475 in Patients with Acute Leukemias

drug called venetoclax. The purpose of this study is to see whether the study drug and venetoclax can work together to slow down the growth of cells that cause acute myeloid leukemia (AML).

blast cells
venetoclax
induction chemotherapy
myeloid leukemia
acute leukemia
  • 4 views
  • 10 Nov, 2021
  • 3 locations
Featured trial
ACCL0993: A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infection in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)

ACCL0993: A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infection in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)

  • 118 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Celgene MDS-AML Registry Connect

Celgene MDS-AML Registry Connect

  • 38 views
  • 08 Nov, 2020
  • 1 location
None
Treating Patients With Childhood Acute Myeloid Leukemia With Interleukin-2

The purpose of this study is to evaluate the interest of maintenance treatment with interleukin-2 by randomizing the patients being not allogeneic transplanted in complete remission after induction and consolidation chemotherapy concerning the event free survival.

myeloid leukemia
remission
  • 14 views
  • 07 Nov, 2020
  • 1 location
None
Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

-M1)." The specific subtype of acute myeloid leukemia will determine which sub-study, within this protocol, a participant will be assigned to evaluate investigational therapies or combinations with

  • 22 views
  • 05 Jul, 2021
  • 18 locations
None
Sustained Treatment-free Remission in BCR-ABL+ Chronic Myeloid Leukemia

The study will investigate in newly diagnosed CP-CML patients the efficacy of NIL frontline therapy vs IM followed by switch to NIL in the case of absence of optimal response as defined by the ELN criteria.

  • 10 views
  • 21 Jan, 2021
  • 38 locations
None
Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years

This study evaluates the effect of different induction courses in children and adolescents with newly diagnosed acute myeloid leukemia. In the first course patients are randomised to receive

  • 26 views
  • 21 Jan, 2021
  • 33 locations
None
Optimization of TKIs Treatment and Quality of Life in Ph+ CML Patients 60 Years in Deep Molecular Response

In this phase III clinical randomized study, "fixed" intermittent administration (one month ON/one month OFF) of TKIs (control arm), will be compared with "progressive" intermittent administration (one month ON/one month OFF for the 1st year; one month ON/two months OFF for the 2nd year; one month ON/three months OFF for …

kinase inhibitor
dasatinib
gleevec
tasigna
imatinib
  • 3 views
  • 31 Jul, 2021
  • 1 location
None
Acute Promyelocytic Leukemia 2006 (APL)

To assess the role of Arsenic trioxide and/or ATRA during consolidation course in APL. It is hoped that the investigational arms will further increase the event-free survival at 2 years, with reduced toxicity and without increasing the relapse rate by comparison with a classical anthracycline-AraC consolidation regimen.

idarubicin
tretinoin
anthracyclines
arsenic
  • 13 views
  • 07 Nov, 2020
  • 1 location
None
Imatinib + MTC in Relapsed / Refractory Acute Myeloid Leukemia (AML)

The purpose of this study is to show superiority in complete responses of combination therapy MTC plus Glivec in patients with refractory or relapsed AML compared to a historical control which was treated with MTC alone.

serum bilirubin level
refractory acute myeloid leukemia (aml)
mitoxantrone
secondary acute myeloid leukemia
  • 15 views
  • 07 Nov, 2020
  • 1 location