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Found 57 clinical trials
Featured trial
  • 0 views
  • 19 Sep, 2022
  • 20 locations
Featured trial
A Phase 2, Open-Label, Monotherapy, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement

This is an open-label, monotherapy study of INCB054828 in subjects with myeloid/lymphoid neoplasms with FGFR1 rearrangement.  Subjects will receive a once daily (QD) dose of INCB054828 at 13.5 mg on a 2-week-on–therapy and 1-week-off–therapy schedule.  With Protocol Amendment 3, the administration schedule will be adjusted, and newly enrolled subjects will …

FGFR1
lymphoid malignancy
myeloid neoplasm
  • 182 views
  • 10 May, 2022
  • 35 locations
Reduced MBF Regimen for Patients Over 50 Years With Myeloid Malignancies

(100mg/m2) in patients with myeloid malignancies including AML, MDS and CMML over 50 years.

  • 0 views
  • 07 Jul, 2022
  • 2 locations
A Phase 2 Multi-Arm Study of Magrolimab Combinations in Patients With Myeloid Malignancies

The primary objectives of this study are to evaluate the safety, tolerability and to determine the recommended Phase 2 dose (RP2D) of magrolimab (Mag) in combination with the anti-leukemia therapies of venetoclax (Ven) and azacitidine (Aza) (Cohort 1), mitoxantrone, etoposide, and cytarabine (MEC) (Cohort 2) and CC-486 (Cohort 3) respectively …

  • 1 views
  • 14 Sep, 2022
  • 21 locations
Post Transplant High-Dose Cy as GvHD Prophylaxis in 1 HLA Mismatched Unrelated HSCT for Myeloid Malignancies

Mismatched (7/8 matched) Unrelated Hemopoietic Stem Cell Transplantation for Myeloid Malignancies.

  • 0 views
  • 27 Aug, 2021
  • 33 locations
A Study to Evaluate the Efficacy and Safety of Roxadustat for the Treatment of Anemia in Participants Receiving Chemotherapy Treatment for Non-Myeloid Malignancies

The main goal of this study is to evaluate the efficacy of roxadustat for treatment of anemia in participants with non-myeloid malignancies receiving multi-cycle treatments of myelosuppressive

  • 0 views
  • 15 Jun, 2022
  • 1 location
Anti-CD33 CAR NK Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia

CAR technology has been used in T cell therapy and gets great success in treating hematological diseases. Following models of CAR T cells, CAR NK cell therapy has been one hot point. For myeloid

hematologic disorder
cell transplantation
cancer
refractory acute myeloid leukemia (aml)
remission
  • 0 views
  • 25 Mar, 2022
  • 1 location
Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

The use of genomics and functional translational studies is to identify and diagnose patients with precursor features of myeloid neoplasms and inherited bone marrow failure syndromes.

  • 6 views
  • 10 Jul, 2022
  • 1 location
  • 0 views
  • 19 Sep, 2022
  • 20 locations
AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms (AVAJAK)

Philadelphia-negative myeloproliferative neoplasms (MPN) are frequent and chronic myeloid malignancies including Polycythemia Vera (PV), essential thrombocythemia (ET), Primary Myelofibrosis

thrombosis
myelofibrosis
cancer
essential thrombocythemia
aspirin
  • 0 views
  • 24 Jul, 2022
  • 1 location