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Found 754 clinical trials
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The Axcelsius Study: A Study of ONO-7475 in Patients with Acute Leukemias

drug called venetoclax. The purpose of this study is to see whether the study drug and venetoclax can work together to slow down the growth of cells that cause acute myeloid leukemia (AML).

cancer
venetoclax
blast cells
refractory acute myeloid leukemia (aml)
leukemia
  • 4 views
  • 23 Jul, 2021
  • 3 locations
featured
ACCL0993: A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infection in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)

ACCL0993: A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infection in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)

  • 112 views
  • 08 Nov, 2020
  • 1 location
featured
Celgene MDS-AML Registry Connect

Celgene MDS-AML Registry Connect

  • 38 views
  • 08 Nov, 2020
  • 1 location
Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

-M1)." The specific subtype of acute myeloid leukemia will determine which sub-study, within this protocol, a participant will be assigned to evaluate investigational therapies or combinations with

  • 22 views
  • 05 Jul, 2021
  • 18 locations
Sustained Treatment-free Remission in BCR-ABL+ Chronic Myeloid Leukemia

The study will investigate in newly diagnosed CP-CML patients the efficacy of NIL frontline therapy vs IM followed by switch to NIL in the case of absence of optimal response as defined by the ELN criteria.

  • 10 views
  • 21 Jan, 2021
  • 38 locations
Treating Patients With Childhood Acute Myeloid Leukemia With Interleukin-2

The purpose of this study is to evaluate the interest of maintenance treatment with interleukin-2 by randomizing the patients being not allogeneic transplanted in complete remission after induction and consolidation chemotherapy concerning the event free survival.

myeloid leukemia
remission
  • 14 views
  • 07 Nov, 2020
  • 1 location
Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years

This study evaluates the effect of different induction courses in children and adolescents with newly diagnosed acute myeloid leukemia. In the first course patients are randomised to receive

  • 26 views
  • 21 Jan, 2021
  • 33 locations
Optimization of TKIs Treatment and Quality of Life in Ph+ CML Patients 60 Years in Deep Molecular Response

In this phase III clinical randomized study, "fixed" intermittent administration (one month ON/one month OFF) of TKIs (control arm), will be compared with "progressive" intermittent administration (one month ON/one month OFF for the 1st year; one month ON/two months OFF for the 2nd year; one month ON/three months OFF for …

nilotinib
kinase inhibitor
dasatinib
tasigna
gleevec
  • 3 views
  • 31 Jul, 2021
  • 1 location
Acute Promyelocytic Leukemia 2006 (APL)

To assess the role of Arsenic trioxide and/or ATRA during consolidation course in APL. It is hoped that the investigational arms will further increase the event-free survival at 2 years, with reduced toxicity and without increasing the relapse rate by comparison with a classical anthracycline-AraC consolidation regimen.

anthracyclines
tretinoin
idarubicin
arsenic
  • 13 views
  • 07 Nov, 2020
  • 1 location
Imatinib + MTC in Relapsed / Refractory Acute Myeloid Leukemia (AML)

The purpose of this study is to show superiority in complete responses of combination therapy MTC plus Glivec in patients with refractory or relapsed AML compared to a historical control which was treated with MTC alone.

refractory acute myeloid leukemia (aml)
secondary acute myeloid leukemia
serum bilirubin level
mitoxantrone
  • 15 views
  • 07 Nov, 2020
  • 1 location