Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 733 clinical trials
featured
A Phase 1b Dose Escalation and Expansion, Multicenter, Open-label, Safety, Pharmacokinetic and Pharmacodynamic Study of APTO-253 in Patients with Relapsed or Refractory Acute Myelogenous Leukemia or High-Risk Myelodysplasia

This study is being done to evaluate the safety and effectiveness of APTO-253 for the treatment of patients with the condition of acute myelogenous leukemia (AML) or myelodysplastic syndrome (MDS

acute leukemia
leukemia
adult acute myelogenous leukemia
cancer
  • 101 views
  • 29 Dec, 2020
  • 8 locations
featured
ACCL0993: A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infection in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)

ACCL0993: A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infection in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)

  • 112 views
  • 08 Nov, 2020
  • 1 location
featured
Celgene MDS-AML Registry Connect

Celgene MDS-AML Registry Connect

  • 38 views
  • 08 Nov, 2020
  • 1 location
Treating Patients With Childhood Acute Myeloid Leukemia With Interleukin-2

The purpose of this study is to evaluate the interest of maintenance treatment with interleukin-2 by randomizing the patients being not allogeneic transplanted in complete remission after induction and consolidation chemotherapy concerning the event free survival.

myeloid leukemia
remission
  • 14 views
  • 07 Nov, 2020
  • 1 location
Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

-M1)." The specific subtype of acute myeloid leukemia will determine which sub-study, within this protocol, a participant will be assigned to evaluate investigational therapies or combinations with

  • 21 views
  • 11 Apr, 2021
  • 18 locations
Sustained Treatment-free Remission in BCR-ABL+ Chronic Myeloid Leukemia

The study will investigate in newly diagnosed CP-CML patients the efficacy of NIL frontline therapy vs IM followed by switch to NIL in the case of absence of optimal response as defined by the ELN criteria.

  • 10 views
  • 21 Jan, 2021
  • 38 locations
Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years

This study evaluates the effect of different induction courses in children and adolescents with newly diagnosed acute myeloid leukemia. In the first course patients are randomised to receive

  • 26 views
  • 21 Jan, 2021
  • 33 locations
Efficacy and Safety of Immunotherapy With Allogeneic Dendritic Cells DCP-001 in Patients With Acute Myeloid Leukaemia

Phase II study to evaluate safety and efficacy of DCP-001 in patients with AML in CR, and with presence of MRD

  • 0 views
  • 12 Feb, 2021
  • 10 locations
Acute Promyelocytic Leukemia 2006 (APL)

To assess the role of Arsenic trioxide and/or ATRA during consolidation course in APL. It is hoped that the investigational arms will further increase the event-free survival at 2 years, with reduced toxicity and without increasing the relapse rate by comparison with a classical anthracycline-AraC consolidation regimen.

idarubicin
arsenic
tretinoin
anthracyclines
  • 13 views
  • 07 Nov, 2020
  • 1 location
Imatinib + MTC in Relapsed / Refractory Acute Myeloid Leukemia (AML)

The purpose of this study is to show superiority in complete responses of combination therapy MTC plus Glivec in patients with refractory or relapsed AML compared to a historical control which was treated with MTC alone.

refractory acute myeloid leukemia (aml)
mitoxantrone
serum bilirubin level
secondary acute myeloid leukemia
  • 15 views
  • 07 Nov, 2020
  • 1 location