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Found 53 clinical trials
Outcomes of MF Patients Exposure to Ruxolitinib During Transplantation

Ruxolitinib treatment prior to transplantation DAC+BF as myeloablative conditioning regimen CSA from day -3 and MMF from day +1 until day 28 ATG Neovii at dose of 7.5mg/KG for mismatch

  • 0 views
  • 26 Jan, 2021
  • 1 location
A Trial to Evaluate Safety and Efficacy of RP-L401-0120 in Subjects With Infantile Malignant Osteopetrosis

The primary objective of this Phase 1 study is to evaluate the therapeutic safety and feasibility of the investigational product (IP), RP-L401.

  • 0 views
  • 15 May, 2021
  • 1 location
Plerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD Patients

Treatment Study to assess of safety and efficiency of conditioning with Plerixafor and G-CSF as additional agents for prevention of graft failure after transplantation in patients with chronic granulomatous disease

gcsf
g-csf
stem cell transplantation
  • 0 views
  • 23 Jan, 2021
  • 1 location
A Safety and Efficacy Study of FCR001 vs Standard of Care in de Novo Living Donor Kidney Transplantation

A randomized controlled study to assess the safety and efficacy and overall benefit of FCR001 cell therapy in de novo living donor renal transplantation.

  • 23 views
  • 08 Mar, 2021
  • 13 locations
Low Dose Treosulfan Based Conditioning Regimen in HSCT for Nijmegen Breakage Syndrome

The aim of the current study is to evaluate the safety and efficacy of low dose treosulfan based conditioning regimen in HSCT in Nijmegen breakage syndrome

  • 0 views
  • 25 Jan, 2021
  • 1 location
Non-Myeloablative Allogeneic Transplantation From Unrelated Donors in Multiple Myeloma

The protocol aims at reducing transplant toxicity and mortality in patients with multiple myeloma.

cell transplantation
  • 4 views
  • 07 Nov, 2020
  • 1 location
A Clinical Study to Assess the Efficacy and Safety of Gene Therapy for the Treatment of Cerebral Adrenoleukodystrophy (CALD)

). Approximately 35 participants will be infused with Lenti-D Drug Product after myeloablative conditioning with busulfan and fludarabine. This trial will evaluate the efficacy and safety of autologous

  • 0 views
  • 27 Jan, 2021
  • 9 locations
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

morphological remission (CR, less than 5% bone marrow blasts, no blasts in cerebrospinal fluid, no other extramedullary leukemia), who have an indication for HSCT with a myeloablative conditioning regimen.

cancer
busulfan
remission
fludarabine
cell transplantation
  • 389 views
  • 25 Jan, 2021
  • 158 locations
International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia

the toxicity and effectiveness of two haemopoietic stem cell transplant (HSCT) conditioning regimens of different intensity: conventional myeloablative conditioning (MAC) with busulfan

induction chemotherapy
fludarabine
mitoxantrone
ejection fraction
daunorubicin
  • 0 views
  • 26 Jan, 2021
  • 59 locations
Haplo vs. URD in AML

This study compares haplo-identical family donor stem cell transplantation (haplo SCT) to matched unrelated donor transplantation (URD SCT) in adult patients with acute myeloid leukemia (AML) with the hypothesis that haplo SCT is as good as URD SCT. Background A haplo-identical family donor is a relative sharing 50% of the …

cell transplantation
cyclophosphamide
busulfan
graft versus host disease
hla-a
  • 4 views
  • 23 Jan, 2021
  • 14 locations