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Found 7 clinical trials
Efficacy and Safety of Mydriatic Microdrops for Retinopathy Of Prematurity Screening

The purpose is to test the hypothesis that microdrop instillation of combined phenylephrine 1.67% and tropicamide 0.33% eyedrops causes at least equal mydriasis compared with standard drop

  • 0 views
  • 27 Oct, 2021
  • 1 location
Cholinergic Mechanisms of Attention in Aging

This study will use an anticholinergic pharmacological probe to examine attention network function in SCD using EEG. The overall hypothesis is that in older adults with SCD, normal cognitive performance is maintained by compensatory attention network activity, supported by enhanced cholinergic function. The investigators anticipate that SCD will be associated …

Accepts healthy volunteers
  • 0 views
  • 20 Jun, 2022
  • 1 location
Safety and Efficacy of rAAV.hCNGA3 Gene Therapy in Patients With CNGA3-linked Achromatopsia

The purpose of this study is to proof the safety and efficacy of a single bilateral subretinal injection of rAAV.hCNGA3 in adult and minor patients with CNGA3-linked achromatopsia.

  • 12 views
  • 10 Apr, 2021
  • 1 location
CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops

CHED- Congenital Endothelial Endothelial Dystrophy is a condition that causes corneal cloudiness. Since, currently only surgery is being done to cure this condition, we are taking up the research of using topical eye drops for this condition which is a very simple and easy method. Also, there are no significant …

  • 6 views
  • 27 Apr, 2021
  • 1 location
Developing a Method to Objectively Measure Opioid Analgesia

Inappropriate prescribing is the fundamental upstream driver of the opioid epidemic. Objective measures to determine the appropriateness of an opioid intervention, provide monitoring of the therapy for adequacy of dose and detection of tolerance or hyperalgesia would eliminate the subjective nature of opioid mediated pain management and obviate iatrogenic facilitation …

  • 28 views
  • 12 Feb, 2022
  • 1 location
Evolution of Oropharyngeal and Rectal Microbiota After Severe Traumatic Brain Injury

Modifications of the human gut microbiota have been associated with different pathological conditions such as obesity, inflammatory bowel diseases and neurodegenerative diseases. Recently the " Brain-Gut Axis ", a bidirectional communication axis between brain and gut, has been described. In recent animal studies, an acute brain injury was associated with …

traumatic brain injury
Accepts healthy volunteers
acute brain injuries
severe traumatic brain injury
coma
  • 0 views
  • 05 Dec, 2021
  • 1 location
Study on the Assessment of Determinants of Muscle and Bone Strength Abnormalities in Diabetes (SAMBA)

This project will assess the independent predictors of impaired muscle and bone strength through a longitudinal observation of a cohort of subjects with type 1 and 2 diabetes consecutively attending an outpatients diabetes clinics for the annual screening of complications.

diabetes
  • 21 views
  • 24 Feb, 2022
  • 1 location