mycophenolate Clinical Research Trials

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Found 140 clinical trials

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Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

, mycophenolate mofetil and prednisone to prevent rejection of the donated cells and to prevent graft-versus-host disease (GVHD), a complication of stem cell transplants in which the donor s immune cells destroy

anemia

myelodysplastic syndromes

anemia studies

aplastic anemia

myelodysplastic syndrome (mds)

48 views
22 Dec, 2020
1 location

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Research Study of ATG and Rituximab in Renal Transplantation (RESTARRT)

1078 views
23 Nov, 2020
5 locations

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A Phase 2 Double-Blind, Placebo Controlled Multi-Center Study to Evaluate the Efficacy and Safety of Tcelna in Subjects With Secondary Progressive Multiple Sclerosis

204 views
08 Nov, 2020
1 location

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A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

248 views
23 Nov, 2020
1 location

Adalimumab vs. Conventional Immunosuppression for Uveitis Trial

Non-infectious intermediate, posterior, and panuveitides are chronic, potentially-blinding diseases. Vision-threatening cases require long-term therapy with oral corticosteroids and immunosuppression. Based upon preliminary data, adalimumab, a fully-human, anti-TNFmonoclonal antibody, now US FDA-approved for uveitis treatment, may be a superior corticosteroid-sparing agent than conventional immunosuppressive drugs. The ADVISE Trial is multicenter randomized, …

prednisone

corticosteroids

monoclonal antibodies

adalimumab

immunosuppressive agents

103 views
13 Aug, 2020
27 locations

Extracorporeal Photopheresis for Medicare Recipients of Lung Allografts

The primary aims of this study is to determine the efficacy and tolerability of Extracorporeal Photopheresis (ECP) for the treatment of either refractory (240) or newly diagnosed (739) Bronchiolitis Obliterans Syndrome (BOS) in patients after lung transplantation.In compliance with the Centers for Medicare and Medicaid Services' (CMS) Coverage with Evidence …

5 views
02 Sep, 2020
21 locations

Mycophenolate Mofetil Versus Azathioprine in Treatment Naive Autoimmune Hepatitis

intolerant for, azathioprine. Mycophenolate mofetil (MMF) has surpassed azathioprine as therapy to prevent organ transplant rejection and is sometimes used as an alternative option for autoimmune hepatitis

liver disease

prednisolone

remission

azathioprine

mycophenolate

26 views
08 Nov, 2020
1 location

Efficacy and Safety of Tacrolimus Versus Mycophenolate in Lupus Nephritis

Prospective, randomized, parallel-group controlled, open-label, international (Asian) multicenter, comparison of corticosteroids combined with TAC and corticosteroids combined with MMF.

nephritis

corticosteroids

tacrolimus

hematuria

proteinuria

67 views
11 Nov, 2020

Mycophenolate Mofetil in Antiretroviral Na ve Patients 2 (MAN2 Study)

The purpose of the study is to evaluate whether mycophenolate mofetil (MMF) can treat the chronic hyperactivation of the immune system and (partly) prevent the decrease of the CD4+ T-cell

AIDS

hiv-1 infection

hiv-1 rna measurement

antiretroviral therapy

antiretroviral agents