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Found 128 clinical trials
Cryotherapy on Inflammatory Profile and Postoperative Pain Levels in Endodontic Infections

The aim of this study is to evaluate the effects of cryotherapy applications on the inflammatory cytokine and collagenase matrix metalloproteinase levels during root canal treatment and postoperative pain intensity and incidence. Mandibular premolar teeth of 60 male patients within the 20-30 years old range, diagnosed with asymptomatic apical periodontitis …

enzyme-linked immunosorbent assay
postoperative pain
  • 26 Aug, 2021
  • 1 location
Intraoral Cryotherapy on Cytokine Levels and Postoperative Endodontic Pain

The aim of this study is to evaluate the effects of intraoral cryotherapy on the inflammatory cytokine levels during root canal treatment and postoperative pain intensity and incidence. Mandibular premolar teeth of 30 patients diagnosed with asymptomatic apical periodontitis will be included to the study for this purpose. The experimental …

enzyme-linked immunosorbent assay
  • 01 Sep, 2021
  • 1 location
Precision Medicine for Sng/Pain Control

Patients have different response to different treatment modalities, and sore/pain medicine is no exception. In our experience, low-level laser (LLL), ultrasound, and prolotherapy can reduce sore /pain through different genetic pathway. Whether the therapeutic effect is controlled by the genetic variants of those sore /pain related genes or not, is …

  • 22 Dec, 2021
  • 1 location
Recovery Kinetics After Different Power Training Protocols (PTRecovery)

Muscle power is one of the most important parameters in almost every athletic action, expressing the ability of the human muscle to produce great amounts of force with the greatest possible speed. For enhancing their muscle power, athletes comprise several resistance training programs as part of their training. However, muscle …

Accepts healthy volunteers
  • 08 Oct, 2021
  • 1 location
Doxycycline vs Isotretinoin for Acneiform Eruptions of TKI

Tyrosine Kinase inhibitors (TKIs) have become standard of care in patients with EGFR mutations in non-small cell lung cancer and other EGFR-mutated cancers. However, TKIs are well-known to cause cutaneous adverse events, including acneiform eruptions. Moderate to severe acneiform eruptions are often associated with severe pruritus and pain. Current treatment …

  • 15 Sep, 2021
  • 1 location
Physiotherapy After Anterior Cervical Spine Surgery

Background: Patients suffering residual disability after anterior decompression and fusion (ACDF) surgery for cervical disc disease may be prescribed physical activity (PPA) or neck-specific exercises (NSE). Currently, we lack data for the success of either approach. There is also a knowledge-gap concerning the use of internet-based care for chronic neck …

neck pain
drug use
rehabilitation program
nerve root compression
  • 27 Feb, 2021
  • 1 location
Botulinum Toxin Injections for Oral Neuropathic Pain

Peripheral painful traumatic trigeminal neuropathy (PPTTN) are poorly relieved by existing treatments which in addition induce many adverse effects. BTX, which blocks the exocytosis of neurotransmitters, can be captured by axonal retrograde transport in primary nociceptive neurons. Injected in the painful area, it might therefore inhibit the release of algogenic …

  • 26 Jan, 2021
  • 1 location
COVID-19 Pneumonitis Low Dose Lung Radiotherapy (COLOR-19)

Low-dose radiotherapy treatment delivered to both lungs in patients with immune-related pneumonia following COVID-19 infection is backed up by biological and clinical bases that justify its use as a possible therapeutic option in these patients. This is a preliminary exploratory study (non-pharmacological interventional) to evaluate the feasibility and tolerability of …

chest ct
  • 25 Jan, 2021
  • 1 location
Dry Needling for Sub Acromial Pain Syndrome

This trial will investigate the benefit of trigger point dry needling (DN) for individuals with a common cause of shoulder pain - sub-acromial pain syndrome. Sub-acromial pain syndrome, also knowns as SAPS, is one of the most common causes of shoulder pain. Physical therapy treatments are routinely used for treating …

shoulder pain
physical therapy treatment
manual therapy
  • 19 Mar, 2021
  • 1 location
Ezetimibe Utilization Early After Acute Myocardial Infarction "EzAMI Trial"

Rationale Patients with acute coronary syndromes are at an increased risk for recurrent adverse coronary events, particularly during the early period following their initial presentation. Early (in-hospital) initiation of high-intensity statins reduces the risk of recurrent events and is therefore recommended by the best current practice guidelines.(1,2) However, the delayed …

myocardial infarction
statin therapy
hmg-coa reductase inhibitors
  • 06 Aug, 2021
  • 1 location