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Found 136 clinical trials
Metabolic Exercise Testing

Exertional symptoms are the hallmarks of metabolic myopathies, supporting the concept of using functional tests when this diagnosis is suspected. Exercise increases the concentration of muscle metabolites in the venous blood supply (e.g. lactate, pyruvate, and ammonia) especially during recovery. The purpose of this study is to compare the results …

muscle biopsy
  • 5 views
  • 24 Jan, 2021
  • 2 locations
Comparison of ME/CFS and Long COVID-19 Patients

The purpose of the You + ME Registry and Biobank is to collect clinical and patient-reported data and biological samples (e.g. blood) from people living with Myalgic Encephalomyelitis (also

  • 67 views
  • 16 Apr, 2021
  • 1 location
Analysis of Immunogenicity, Safety and Efficacy of COVID-19 Vaccines in Immunosuppressed Individuals

(fever, fatigue, headache, chills, vomiting, diarrhea, new or worsened muscle pain, and new or worsened joint pain) occurring up to 7 days following each vaccine dose will be systematized and compared

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
Long COVID Kids DK - Investigating Long-term Covid-19

their children experience gastrointestinal issues, chest pain, headaches, fatigue, joint/muscle pain, sore throat, dizziness, nausea and fever for months following COVID-19 infection. In this

  • 0 views
  • 29 Dec, 2021
  • 1 location
Molecular Basis of Erythrocyte Invasion by Plasmodium Vivax Into Duffy-Negative Erythrocytes in Mali

Background Malaria is caused by parasites carried by some mosquitos. When the mosquitos bite people, the parasites can infect them. One of these parasites is Plasmodium vivax (P. vivax). Some children have P. vivax in their blood. They did not have malaria symptoms, but some also had a blood problem …

anemia
Accepts healthy volunteers
  • 0 views
  • 25 Jul, 2022
  • 2 locations
Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health

Background People who get COVID-19 have a wide range of symptoms. They also recover from COVID-19 in different ways. In this study, researchers will use survey data to describe the different ways people experience and recover from COVID-19. They will also use the data to help create future studies to …

  • 2 views
  • 22 Jul, 2022
  • 1 location
Italian Treatment Free Remission Registry

The investigator propose an extension of the previous National, multicentric study, promoting an observational registry, both retrospective and prospective, in order to expand and further characterize the series of Italian patients with Philadelphia-positive, chronic phase CML (CP-CML) who discontinue TKIs in an off-protocol setting. As safety concerns may arise for …

chronic phase chronic myeloid leukemia
interferon
Accepts healthy volunteers
remission
  • 0 views
  • 26 Nov, 2021
  • 1 location
Immunization of 7 Different Vaccines Against SARS-COV-2 Across 4 Countries.

Background: Scarce information exists in relation to the comparison of seroconversion and adverse events following immunization (AEFI) with different SARS-COV2 vaccines. Our aim was to correlate the magnitude of the antibody response to vaccination with previous clinical conditions and AEFI. Methods: A multicentric comparative study where SARS-CoV-2 spike 1-2 IgG …

Accepts healthy volunteers
  • 0 views
  • 25 Apr, 2022
  • 1 location
Frequency of Pompe Disease in Patients With Myalgia With or Without Hyper Ckemia - Data From the Reference Center (CERCA)

Pompe's disease is a lysosomal storage disease of autosomal recessive genetic transmission due to a deficiency in acid alpha glucosidase. This enzyme deficiency leads to glycogen overload in all cells but with a more marked expression in muscle cells. There is a great variability in the clinical manifestations and in …

replacement therapy
deficiency
  • 0 views
  • 03 Nov, 2021
  • 1 location
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in ME/CFS

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

encephalomyelitis
fatigue
  • 531 views
  • 01 Mar, 2022
  • 1 location