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Found 7 clinical trials
PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study

The primary objective of this study is to evaluate several interventions given to participants with severe asthma. Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.

methacholine
corticosteroids
albuterol
bronchodilator
  • 194 views
  • 04 Oct, 2022
  • 28 locations
Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

Background In people with multiple sclerosis (MS), brain and cerebrospinal fluid (CSF) biomarkers indicate inflammation or disease. Researchers want to see if 4

natalizumab
dimethyl fumarate
mitoxantrone
ocrelizumab
copaxone
  • 34 views
  • 25 Oct, 2022
  • 1 location
Precision Medicine for Sng/Pain Control

precision medicine for sore /pain control via the genetic markers. Investigators will recruit 80 myofascial pain patients from Department of Physical Medicine and Rehabilitation, National Taiwan University

  • 0 views
  • 22 Dec, 2021
  • 1 location
Study of Anti-Malarials in Incomplete Lupus Erythematosus

This project is a multicenter, randomized, placebo-controlled, double-blind clinical trial that is designed to test whether treating patients who are at risk for development of lupus with hydroxychloroquine can slow accumulation of disease features. Effects on clinical progression of symptoms, patient-reported outcomes and changes in the immune markers of response …

antimalarials
hydroxychloroquine
lupus
antinuclear antibody
arthritis
  • 118 views
  • 09 Nov, 2021
  • 7 locations
Prospective Investigation of Multiple Sclerosis in the Three Rivers Region (PROMOTE)

In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and

nervous
MRI
neurological disorder
disease or disorder
chronic disease
  • 18 views
  • 24 Feb, 2022
  • 1 location
Retrospective and Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System Via a Live Registry (Yale-HF)

The Yale HF Registry is a live EHR based registry that allows for retrospective and real-time monitoring of Heart Failure case across the Yale New Haven Health System.

heart failure
  • 1 views
  • 20 Oct, 2022
  • 1 location
Kidney Precision Medicine Project (KPMP)

Acute kidney injury (AKI) and chronic kidney disease (CKD) impose a significant global health burden. Yet, no effective therapies currently exist for AKI, and only a few are available for CKD. Despite significant effort from industry and academia, development of pharmacologic therapies for AKI and CKD has been hampered by: …

glomerular filtration rate
acute tubular necrosis
proteinuria
diabetes
chronic kidney disease
  • 4 views
  • 04 Jun, 2022
  • 8 locations