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Found 57 clinical trials
Featured trial
A Study of TAK-341 in Treatment of Multiple System Atrophy

The main aim is to see how TAK-341 works after 52 weeks in participants with multiple system atrophy as measured by the Unified Multiple System Atrophy Rating Scale Part I (UMSARS).

  • 9 views
  • 14 Dec, 2022
  • 1 location
Featured trial
New Approaches to Dementia Heterogeneity.

This study is looking for adults who have mild cognitive impairment, Alzheimer’s, or other forms of dementia. The study is also looking for people with normal cognition, as a comparison. The study is interested in the ways that brain function changes over time with the goal of improving the ability to diagnose …

heart disease
depression
dementia, frontotemporal
dementia
aphasia
  • 160 views
  • 25 May, 2021
  • 1 location
Spinal Cord Stimulation Therapy for Freezing of Gait in Parkinson's Syndrome Patients

Spinal cord stimulation may be a new therapeutic approach for freezing of gait. It's a multi-center, prospective, open label clinical study with a 12 months follow-up period, to investigate the therapeutic effect and safety of spinal cord stimulation for freezing of gait in patients with advanced Parkinson's disease and Parkinsonism-Plus …

  • 0 views
  • 28 Jan, 2021
  • 1 location
Trial of Parkinson's And Zoledronic Acid (TOPAZ)

This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 3500 participants will …

dementia
osteoporosis
Accepts healthy volunteers
vascular parkinsonism
cognitive assessment
  • 256 views
  • 12 May, 2022
  • 53 locations
Community Outreach for Palliative Engagement -- Parkinson Disease (COPE-PD)

The purpose of this study is to learn more about the effectiveness of palliative care training for community physicians and telemedicine support services for patients and carepartners with Parkinson's disease and Lewy Body Dementia (LBD) or related conditions and their care partners. Palliative care is a treatment approach focused on …

depression
dementia
Accepts healthy volunteers
progressive supranuclear palsy
parkinsonism
  • 3 views
  • 10 May, 2022
  • 1 location
The Swedish BioFINDER 2 Study (BioFINDER2)

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

amyloid
dementia
Accepts healthy volunteers
tauopathies
brain imaging
  • 178 views
  • 25 Feb, 2022
  • 1 location
Insulin Resistance in Multiple System Atrophy (IRAMS)

Multiple system atrophy (MSA) is a rare and fatal neurodegenerative disorder. The pathologic hallmark is the accumulation of aggregated alpha-synuclein in oligodendrocytes forming glial

alpha-synuclein
insulin
Accepts healthy volunteers
insulin resistance
  • 5 views
  • 23 Apr, 2022
  • 1 location
GDNF Gene Therapy for Multiple System Atrophy

subjects with either a possible or probable diagnosis of Multiple System Atrophy.

  • 4 views
  • 04 Oct, 2022
  • 1 location
Spinal Cord Stimulation for Multiple System Atrophy

previous research, this study first proposes an innovative treatment protocol for multiple system atrophy with SCS in C2-4 segment. We intend to conduct a prospective single-center open clinical trial to

orthostatic hypotension
  • 0 views
  • 23 Mar, 2022
  • 1 location
A Study of Lu AF82422 in Participants With Multiple System Atrophy (AMULET)

To find out the effect of Lu AF82422 on disease progression in participants with multiple system atrophy.

  • 2 views
  • 04 Oct, 2022
  • 17 locations