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Found 146 clinical trials
Effectiveness of Photobiomodulation Protocols in Radiation-induced Oral Side Effects in H&N Cancer Patients

oral sequelae such as oral mucositis (OM), dysgeusia, opportunistic infections, trismus, and xerostomia/hyposalivation can affect HNC patients due to oncological treatment with RT and QT

head and neck cancer
cancer
neck cancer
  • 0 views
  • 25 Mar, 2022
  • 1 location
Peri-implantitis Implantoplasty Treatment

This double arm, split-mouth, single centre, controlled, randomised clinical study is designed to examine the effect of implantoplasty in treatment of peri-implantitis. Peri-implantitis will be treated with open flap debridement, with or without implantoplasty.

Accepts healthy volunteers
debridement
  • 0 views
  • 08 Jun, 2022
  • 2 locations
A Phase IIa, Multi-center, Dose-finding Study to Evaluate Safety and Efficacy for Prevention of Oral Mucositis and PK of MIT-001 in Patients With Lymphoma or Multiple Myeloma Receiving Conditioning Chemotherapy Followed by Auto HSCT (Capella)

Evaluate the efficacy and safety for the prevention of oral mucositis and PK of MIT-001 for lymphoma or multiple myeloma patients receiving conditioning chemotherapy for autologous hematopoietic

  • 0 views
  • 27 Oct, 2022
  • 2 locations
The Effectiveness of a Thyme and Honey Spray for Oral Toxicities

Aim: To evaluate the effectiveness of thymus honey on radiation induced-oral mucositis and xerostomia. Background: Oral mucositis and xerostomia are two of the most severe side effects

induction chemotherapy
mucositis
  • 0 views
  • 17 Dec, 2021
  • 1 location
Evaluation of an Oral Care Programme for Head and Neck Cancer Patients

This study will evaluate the effect of an intensified oral care programme on prevalence, severity and duration of mucositis in patients undergoing treatment for cancer in the head and neck

mucositis
  • 17 views
  • 01 Mar, 2022
  • 1 location
MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients (MIT-001)

of MIT-001 compared to the placebo in prevention of oral mucositis (OM) in patients with HNSCC who are undergoing concurrent chemoradiotherapy (CCRT).

  • 0 views
  • 21 Mar, 2022
  • 6 locations
Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy

This study aims to propose an alternative and auxiliary methodology for the prevention and treatment of Oral Mucositis (OM) in patients undergoing radiotherapy or radio and chemotherapy for head

carcinoma
oral cancer
head and neck neoplasms
mucositis
intensity-modulated radiation therapy
  • 0 views
  • 23 Apr, 2022
  • 1 location
Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor Transplantation

previous observations with a small modification (melphalan dose reduction due to previous mucositis rates with higher doses), this will be a phase II study designed to measure disease-free-survival.

blast crisis
remission
blast cells
cancer
intrathecal chemotherapy
  • 12 views
  • 22 Mar, 2022
  • 1 location
Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant

engraftment, graft versus host disease, neutrophil count, and incidence and severity of mucositis (inflammation of the mouth or gut) and infection. This study has two cohorts. The first cohort is subjects

myelofibrosis
cell transplantation
ejection fraction
fludarabine
chronic myeloid leukemia
  • 42 views
  • 26 May, 2022
  • 1 location
PROGRESS Trial - Prophylactic Gabapentin for Relief of Symptoms and Improved Swallowing

with Common Terminology Criteria for Adverse Events (CTCAE) grade 2 oral mucositis after receiving definitive nonoperative locoregional therapy with or without prophylactic gabapentin as part of best

gabapentin
cancer
mucositis
oropharyngeal cancer
opioid
  • 11 views
  • 26 Feb, 2022
  • 1 location