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Found 11 clinical trials
The IPLA-OVCA Trial Intra-Peritoneal Local Anaesthetics in Ovarian Cancer

Surgery and chemotherapy combined constitute first line treatment in women with advanced ovarian cancer. The aim of surgery apart from staging is cytoreduction, i.e. surgical resection of tumour. Radical resection of all tumour visible by the naked eye followed by adjuvant chemotherapy is associated with best chance of prolonged survival. …

cytoreductive surgery
ovarian cancer stage
cancer of the ovary
fallopian tube
  • 30 Jan, 2021
  • 1 location
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

small intestine, colon, rectum, pancreas) (closed to accrual 10/17/2018) Fibromixoma and low grade mucinous adenocarcinoma (pseudomixoma peritonei) of the appendix and ovary (closed to accrual

other cancer
lung cancer
  • 11 May, 2022
  • 767 locations
A Clinical Study of Exploring Camrelizumab in the Treatment of Colorectal Mucinous Adenocarcinoma(MAC)

of metastatic colorectal mucinous adenocarcinoma(MAC).

neutrophil count
adjuvant therapy
  • 24 Jan, 2021
  • 1 location
Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

This phase II trial compares how well nivolumab with or without ipilimumab works to shrink cancer masses and prevent additional growth in patients with deficient mismatch repair system (MMR) endometrial cancer that has come back after a period of improvement (recurrent). Deoxyribonucleic acid (DNA) mismatch repair (MMR) is a system …

  • 12 May, 2022
  • 2 locations
The Effects of Moderate Exercise on Distress, Quality of Life, and Biomarkers of Angiogenesis and Chronic Stress in Ovarian Cancer Survivors

Many individuals with ovarian cancer experience distress, fatigue, weakness, anxiety, and other symptoms that decrease quality of life. Moderate exercise may improve quality of life, decrease distress, and improve biomarkers associated with prognosis in individuals with ovarian cancer. This clinical trial studies how well moderate exercise works in improving distress, …

endometrioid carcinoma
cancer of the ovary
fallopian tube
cancer chemotherapy
ovarian cancer
  • 11 Feb, 2022
  • 1 location
Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

This phase II trial studies the possible benefits of treatment with different combinations of the drugs durvalumab, olaparib and cediranib vs. the usual treatment in patients with ovarian, primary peritoneal, or fallopian tube cancer that has come back after a period of improvement with platinum therapy (recurrent platinum resistant). Usual …

  • 16 May, 2022
  • 148 locations
MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian, Fallopian, or Peritoneal Cancer

This randomized phase II trial studies how well oncolytic measles virus encoding thyroidal sodium iodide symporter (MV-NIS) compared to investigator's choice chemotherapy works in treating patients with ovarian, fallopian, or peritoneal cancer. Measles virus, which has been changed in a certain way, may be able to kill tumor cells without …

cytotoxic chemotherapy
neutrophil count
primary tumor
fallopian tube
  • 24 Apr, 2022
  • 3 locations
Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers

This phase I trial studies the side effects and best dose of nab-paclitaxel and bevacizumab in treating patients with stage IV melanoma that cannot be removed by surgery (unresectable), cancer of the cervix, endometrium, ovary, fallopian tube or peritoneal cavity. Drugs used in chemotherapy, such as nab-paclitaxel, work in different …

neutrophil count
biomarker analysis
fallopian tube
  • 04 May, 2022
  • 4 locations
Phase III Trial of Stage I Ovarian Cancer After Surgery

To compare the Overall survival of adjuvant chemotherapy versus observation in stage I epithelial ovarian cancer after comprehensive staging surgery

  • 23 Jan, 2021
  • 103 locations
Clinical Application of Fibroblast Activation Protein PET/MRI for Diagnosis and Staging in Malignant Tumors

Positron emission tomography (PET) molecular imaging provides a valuable tool for the diagnosis and differential diagnosis, staging of various tumors. Malignant tumor is composed of tumor cells and tumor stroma, which occupies the vast majority of the tumor. Cancer-associated fibroblasts (CAF) are an important part of the tumor stroma. Fibroblast …

cancer diagnosis
pet/ct scan
primary cancer
  • 26 Mar, 2022
  • 1 location