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Found 4 clinical trials
Autonomic Determinants of POTS - Pilot 2

study is to determine the importance of sympathetic activation as a cause of orthostatic symptoms. The investigators will assess the effects of a blood pressure medication (Moxonidine) on the symptoms

  • 27 views
  • 04 Oct, 2022
  • 1 location
Autonomic Determinants of POTS - Pilot1

symptoms. The investigators will assess the effects of a blood pressure medication (Moxonidine) on the symptoms during standing. Moxonidine lowers sympathetic activity. The investigators believe patients

Accepts healthy volunteers
moxonidine
orthostatic hypotension
  • 43 views
  • 24 Mar, 2022
  • 1 location
Sympathoinhibition as a Preferred Second Line Treatment of Obesity Related Hypertension (OHT)

This study is designed to investigate whether sympathoinhibition with moxonidine could provide added metabolic benefit compared to the second line therapy in the current guidelines.

body mass index
ace inhibitor
amlodipine 5 mg
hypertension
amlodipine
  • 19 views
  • 16 Oct, 2022
  • 1 location
Sympathetic Mechanisms in Obesity-Crossover Design

different occasions after two weeks of receiving either placebo, amlodipine (vasodilator arm) or moxonidine (study arm). The order of the studies will be determined using computer-generated randomization

hypertension
body mass index
amlodipine
antihypertensive drugs
  • 0 views
  • 13 Jun, 2022
  • 1 location