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Found 138 clinical trials
MST for Parkinson's Disease (MST-PD)

This trial aims to test the feasibility of Magnetic Seizure Therapy (MST) for Depression in patients diagnosed with Parkinson's Disease.

depression
depressed mood
depressive episode
severe depression
  • 5 views
  • 25 Jan, 2022
  • 1 location
Periodic Leg Movements' Diagnosis in Spinal Cord Injury: Actigraphy as an Alternative for Polysomnography?

Periodic Limb Movements during Sleep (PLMs) are episodes of repetitive, stereotypical, hallux or foot movements. They could induce sleep disturbance, fatigue, daytime sleepiness and impaired quality of life but also increased cardiovascular risk by rising heart rate and blood pressure at night. Gold standard for PLMs diagnosis is based on …

multiple sclerosis
spinal cord disorder
spinal cord
  • 0 views
  • 24 Jul, 2021
  • 1 location
Modulating Movement Intention Via Cortical Stimulation

The purpose of this protocol is to learn about movement intention and volition. To improve such knowledge, investigators will conduct sub-studies using multiple non-invasive methodologies. These results could provide preliminary data for subsequent studies evaluating local and global efficacy of plasticity-inducing treatments for PMD symptoms.

Accepts healthy volunteers
  • 13 views
  • 12 Jul, 2022
  • 1 location
A Phase 2 Multicenter, Randomized, Double-blind, Placebo-controlled Study of BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex for the Treatment of Upper Limb Essential Tremor

Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tasks such as writing, pouring, and eating, and

  • 0 views
  • 21 Oct, 2022
  • 13 locations
Dystonia Image-based Programming of Stimulation: A Prospective, Randomized, Double-blind Crossover Trial (DIPS)

a heterogeneous group of movement disorders that share the core clinical feature of abnormal involuntary muscle contractions in common. Pallidal DBS is an established therapy for severe cases with

brain stimulation
  • 0 views
  • 07 Oct, 2022
  • 1 location
Novel DBS Stimulation Patterns for Treatment of Parkinson's Disease - UNMC/Medtronic Collaborative Acute Feasibility Pilot

with the Medtronic Percept PC for the treatment of PD, and who are optimized for clinical stimulation and anti-Parkinsons medication. Investigations will be performed in UNMC Movement Disorders Clinic

depression
motor symptoms
Accepts healthy volunteers
dementia
brain stimulation
  • 0 views
  • 27 Oct, 2022
  • 1 location
Effect of the Visual Information Change in Functional Dystonia (PRISMADYS)

Cervical dystonia occurring only during the writing task is a rare form for which there is no established treatment. Many authors agree that alteration of sensory integration is associated with dystonia. Similar disturbances in the integration of oculomotor information could have a role in cervical dystonia forms involving visuo-cervico-manual coordination …

dystonia
Accepts healthy volunteers
movement disorder
orthoptic treatment
sensory integration
  • 52 views
  • 04 Oct, 2022
  • 1 location
Effects of Individualized Accurate Positioning TMS Based on Task fMRI Activation on Upper Extremity Function After Stroke

motor area is to measure hotspot, which is used as a common target for movement disorders such as hemiplegia after stroke. In the 1990s, the hands-on task activation point determined by functional

  • 0 views
  • 12 Jul, 2022
  • 1 location
tDCS on Parkinson's Disease Cognition (tDCS-PD-fMRI)

Parkinson's disease (PD) has been classically regarded as a "movement disorder", so earlier work has focused on treating motor symptoms only. As PD patients now have longer life expectancy, the

transcranial direct current stimulation
motor symptoms
cholinesterase
cognitive impairment
demented
  • 169 views
  • 20 Apr, 2022
  • 1 location
Deep Brain Stimulation in Patients With Incomplete Spinal Cord Injury for Improvement of Gait (DBS-SCI)

under MLR deep brain stimulation (DBS). Even rats with only 2-10% spared white matter regained weight supporting stepping. DBS is a clinical standard treatment option in patients with movement disorders

incomplete spinal cord injury
spinal cord disorder
electrical stimulation
injuries
spinal cord
  • 91 views
  • 08 Jun, 2022
  • 1 location