Found 102 clinical trials
A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (LIGHTHOUSE)
>Part II measures motor experiences of daily living. Part III is the results of a motor symptoms exam by a medical professional. Part IV records PD complications caused by motor
- 1 views
- 16 Nov, 2022
- 2 locations
Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease
This study is a single-site, double-blinded, randomized clinical trial designed to elucidate mechanism(s) of action for symptomatic benefits observed in Parkinson's disease (PD)
- 17 views
- 04 Oct, 2022
- 1 location
Non-Invasive Brainstem Modulation for the Treatment of Non-Motor Symptoms in Parkinson’s Disease: A Randomized Controlled Trial (RCT) and an Open Label Extension (OLE) Study
The purpose of this research is to understand how a non-invasive neuromodulation device affects adults diagnosed with Parkinson’s disease (PD). A non-invasive device is a device that stays outside of the body. It is not implanted and does not penetrate the skin. Neuromodulation means that the device stimulates activity in …
- 0 views
- 10 Nov, 2022
- 1 location
Perceptual Predictors of Visual Hallucinations in Parkinson's Disease
Visual hallucinations (VH) are among the most distressing of the non-motor symptoms of Parkinson's disease (PD). The investigators plan to examine the relation of perceptual variables-basic
- 0 views
- 04 Oct, 2022
- 1 location
Efficacy and Safety of Astragalus for Non-motor Symptoms of Parkinsonism
Parkinsonism is a cluster of neurodegenerative disease with motor and non-motor symptom. However, there is still a lack of research on the treatment for non-motor symptoms of Parkinsonism
- 0 views
- 07 Oct, 2022
- 1 location
The Effect of Repetitive Transcranial Magnetic Stimulation on the Cognition in People With Parkinson's Disease
dementia are also one of the key features of the non-motor symptoms of PD. At present, the mainstream treatment of PD-dementia is the dopaminergic rivastigmine. Repetitive transcortical magnetic
- 0 views
- 13 Apr, 2021
- 1 location
Telemedicine in Functional Motor Disorder (TeleFMD)
treatment followed by a telemedicine program on the motor, non-motor symptoms (pain, fatigue, anxiety, and depression), the self-perception of clinical change and Health-Related Quality of Life, and health
- 3 views
- 14 May, 2022
- 1 location
Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in People With Parkinson's Disease
different motor symptoms, mainly on the bradykinesia and rigidity but not gait. The present study would like to test the accumulative effect of rTMS on gait disorders of PD, especially the phenomenon of FOG
- 0 views
- 11 Apr, 2021
- 1 location
Mirror Therapy Rehabilitation for Motor Functional Neurological Disorders.
Motor functional neurological disorders (FND) correspond to motor symptoms that are unexplained by an organic lesion but are due to cerebral dysfunction. Patients with these disorders have high
- 0 views
- 08 Aug, 2021
- 1 location
Phase II Trial of Non-Invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Disorders
Background Functional movement disorders (FMD) involve involuntary movements that are not due to a recognized neurological or medical cause. FMD can cause major disability. Researchers want to learn more to create better treatments for FMD. Objective To test whether non-invasive brain stimulation using transcranial magnetic stimulation (TMS) improves FMD symptoms. …
- 0 views
- 21 Oct, 2022
- 1 location