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Found 289 clinical trials
Preemptive Use of the Nicotine Patch for Postoperative Pain Relief After Open Abdominal Surgery

The efficacy of a low dose nicotine patch of seven milligrams placed before surgery and its effect on decreasing pain after surgery is the main purpose of the study.

postoperative pain relief
anesthesia
abdominal operation
pain relief
  • 89 views
  • 07 Nov, 2020
  • 1 location
Effect of Regional Anesthesia on Enhanced Recovery After Spine Surgeries

This study will be carried out on 80 patients who will be presented for different spine surgeries under general anesthesia and regional anesthesia technique in Tanta university hospitals. The study was approved by the research ethics committee of the faculty of medicine. Patients will be admitted to the OR where …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Pectoralis and Serratus Muscle Blocks

The overall research plan is PECS/SAP blocks with liposomal bupivacaine improve the Overall Benefit Analgesia Score averaged over the postoperative days 1, 2, and 3. A 2-point reduction in OBAS will be considered the minimal clinically important benefit.

  • 0 views
  • 28 Jan, 2021
  • 1 location
Propacetamol to Reduce Post Cesarean Section Uterine Contraction Pain

To evaluate that perioperative regular usage of propacetamol to reduce post cesarean section uterine contraction pain and opioid consumption

  • 0 views
  • 06 Sep, 2021
  • 1 location
The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric

Oxycodone is an oral opioid analgesic that is most commonly prescribed for the management of pain in post-operative patients at Boston Children's Hospital. Oxycodone has been widely used in adults and children to relieve post-operative pain. However, its pharmacokinetics (what it does in the body) and pharmacodynamics (how it works) …

  • 0 views
  • 18 Jul, 2021
  • 1 location
Epidural Nalbuphine Versus Dexmedetomidine as Adjuvants to Bupivacaine in Lower Limb Surgeries

Combined spinal epidural anesthesia (CSE) with bupivacaine alone is not sufficient to cover pain sequel during lower limb surgeries. Previous studies used addition of either Nalbuphine or dexmedetomidine to bupivacaine in epidural anesthesia giving a good result in pain control. In this study the investigators will evaluate and compare the …

  • 0 views
  • 19 Sep, 2021
  • 1 location
Dexamethasone Administered Via the Epidural Catheter as an Adjunct in Patients Undergoing Cesarean Delivery

This study will evaluate the ability of dexamethasone to enhance labor epidurals when administered as an adjunct to local anesthetics via an epidural catheter. Patients undergoing elective cesarean sections will be randomized into three groups, each receiving the same combined spinal epidural (CSE). At surgical closure, Group 1 will receive …

  • 3 views
  • 01 Sep, 2021
  • 1 location
Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia

The purpose of this study is to evaluate whether using ultra-low dose naloxone, an opioid antagonist, has the potential to block remifentanil-induced hyperalgesia and tolerance following surgery. There are 3 study groups: (1) low dose remifentanil (LO, 0.1 micrograms/kg/mL), (2) high dose remifentanil (0.4 mg) combined with placebo (HI, 0.4 …

spinal fusions
remifentanil
opioid antagonist
opioid
  • 8 views
  • 15 May, 2021
  • 1 location
Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery

Postoperative ileus, defined as the transient postoperative functional inhibition of propulsive bowel activity, commonly occurs in patients after cardiac surgery and contributes to postoperative morbidity. Naloxegol is a peripheral opioid receptor antagonist. Recent studies showed that naloxegol is effective in the treatment of chronic opioid-induced constipation but there is no …

  • 0 views
  • 08 Aug, 2021
  • 1 location
Benefit of ESP Peri Operative Analgesia for Live Liver Donor Transplantation

Liver donors have a significant risk to develop persistent and chronic pain around 20 to 30% affecting social and professional life (17%) up to 1 year after the surgery. To donate a part of liver is a beautiful gift reason why the pain relief must be improved. Meta-analysis showed that …

  • 0 views
  • 27 Jan, 2021
  • 1 location