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Found 276 clinical trials
Pectoralis and Serratus Muscle Blocks

The overall research plan is PECS/SAP blocks with liposomal bupivacaine improve the Overall Benefit Analgesia Score averaged over the postoperative days 1, 2, and 3. A 2-point reduction in OBAS will be considered the minimal clinically important benefit.

  • 0 views
  • 28 Jan, 2021
  • 1 location
Propacetamol to Reduce Post Cesarean Section Uterine Contraction Pain

To evaluate that perioperative regular usage of propacetamol to reduce post cesarean section uterine contraction pain and opioid consumption

  • 0 views
  • 25 Jan, 2021
  • 1 location
The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric

Oxycodone is an oral opioid analgesic that is most commonly prescribed for the management of pain in post-operative patients at Boston Children's Hospital. Oxycodone has been widely used in adults and children to relieve post-operative pain. However, its pharmacokinetics (what it does in the body) and pharmacodynamics (how it works) …

  • 0 views
  • 24 Jan, 2021
A Pilot Study of Ultra Rapid Opioid Rotation and Titration of Oxymorphone

This project will explore the safety and feasibility of performing a successful intravenous patient controlled analgesia (IV PCA) Oxymorphone titration and conversion to oral ER Oxymorphone (extended release or OPANA ER) in the outpatient setting.

oxycodone
chronic pain
opioid
morphine
analgesia
  • 302 views
  • 08 Nov, 2020
  • 1 location
Benefit of ESP Peri Operative Analgesia for Live Liver Donor Transplantation

Liver donors have a significant risk to develop persistent and chronic pain around 20 to 30% affecting social and professional life (17%) up to 1 year after the surgery. To donate a part of liver is a beautiful gift reason why the pain relief must be improved. Meta-analysis showed that …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery

Postoperative ileus, defined as the transient postoperative functional inhibition of propulsive bowel activity, commonly occurs in patients after cardiac surgery and contributes to postoperative morbidity. Naloxegol is a peripheral opioid receptor antagonist. Recent studies showed that naloxegol is effective in the treatment of chronic opioid-induced constipation but there is no …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Comparison of an Inhaled Sedation Strategy to an Intravenous Sedation Strategy in Intensive Care Unit Patients Treated With Invasive Mechanical Ventilation

The objective of the study is to determine the impact on the frequency of occurrence of delirium of an early inhaled sedation strategy (from induction in rapid sequence if intubation in intensive care, or from admission if intubated in pre -hospital) by Isoflurane using an ANACONDA type system, compared to …

  • 0 views
  • 27 Jan, 2021
  • 8 locations
Aalgesic Efficacy of Erector -Spinae Technique With Levobupvicaine in Patients Undergoing Upper Abdominal Cancer Surgery

To study analgesic efficacy &safety of bilateral erector spinae block for upper abdominal cancer surgery as apart of multimodal analgesia.

  • 0 views
  • 24 Jan, 2021
  • 1 location
Perioperative Analgesia by ESP Catheter on Recipient for Liver Transplantation

Enhanced recovery after surgery (ERAS) programs were developed by Prof Henrik Kehlet in Denmark to reduce the hospitalization and improve the surgical outcomes. In these programs pain relief by regional analgesia techniques are highly recommended to reduced as much as possible the opioids used with their side effects. This program …

  • 0 views
  • 17 Apr, 2021
  • 2 locations
Towards Enhanced Recovery After Cesarean

One in 300 women will become persistent opioid users after cesarean delivery (1). Cesarean delivery is the most common surgical procedure in the United States, representing 31.9% of the 3,788,235 deliveries in 2018 (2). Patients have to cope with the pain and challenges of post-operative care while adjusting to motherhood …

  • 0 views
  • 19 Mar, 2021
  • 1 location