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Found 151 clinical trials
Lifestyle Counseling and Medication for Adolescent Weight Management (QUEST)

The prevalence of adolescent severe obesity is at an all-time high in the United States and the refractory nature of this disease has led to a serious and challenging conundrum in terms of how

  • 17 Mar, 2022
  • 1 location
Nutritional Stimulation of Muscle Protein Synthesis and Metabolic Rate After Bariatric Surgery

Bariatric surgery is an effective treatment for severe obesity but results in loss of muscle mass. The investigators will test the hypothesis that consumption of an Essential Amino Acid-based

sleeve gastrectomy
bariatric surgery
protein supplement
  • 10 Oct, 2022
  • 1 location
Transverse Supraumbilical Versus Pfannenstiel Incision For Cesarean Section In Morbidly Obese Women

cesarean section is one of the most common operative procedures performed in modern obstetrics, that become increasingly common in both developed and developing countries for a variety of reasons today, thus any useful refinement in the operative technique, however minimal, is likely to yield substantial benefits. In morbidly obese women …

Accepts healthy volunteers
  • 09 Jun, 2022
  • 1 location
Laxative Properties of Microencapsulated Lipid (Constipation Study)

The present study seeks to build on these observations to assess whether in principle, fat containing microcapsules might help patients experiencing constipation in association with weight loss interventions (including GLP-1 analogues or bariatric surgery) to both avoid/treat constipation and simultaneously optimise their ability to feel full during eating. This potential …

chronic constipation
Accepts healthy volunteers
other laxatives
  • 13 Jun, 2022
  • 1 location
The Effect of Blood Flow Restriction Training on Hamstring Elasticity After Injury

The aim of this study is to investigate the effect of Blood Flow Restriction Training on the elasticity of the hamstring muscle after an acute injury. Therefore a group of football players with a recent hamstring strain injury (HSI) will be recruited and randomly assigned in one of the three …

  • 20 Aug, 2021
  • 1 location
Young Adults With Early-onset Obesity Treated With Semaglutide -The RESETTLE Study (RESETTLE)

Introduction: Obesity prevalence is particularly pronounced among adolescents. Currently available treatment options consists of structured lifestyle interventions. However, 25 % of adolescents do not respond to lifestyle treatment, why new effective treatment strategies are needed. Therefore, the aim of this study is to investigate the effect of lifestyle interventions combined …

Accepts healthy volunteers
  • 22 Oct, 2022
  • 1 location
Prognostic Significance of Fatty Liver Disease in Bariatric Patients (PROMETHEUS)

Prospective non-randomized intervention case control study on patients with a BMI > 35. The intervention group/cases (n=600) is comprised of bariatric patients who undergo bariatric surgery and the control group (n=600) of age, weight and comorbidity matched patients who choose not to undergo bariatric surgery. The overall aim is to …

bariatric surgery
liver disease
fatty liver
  • 20 Apr, 2022
  • 1 location
Different Limb Lengths in Gastric Bypass Surgery

Obesity and type 2 diabetes mellitus (T2DM) are reaching epidemic proportions in the developed world. In morbidly obese patients only surgical treatment (bariatric operations) leads to a sustained weight loss and relief of co-morbidities in the majority of patients. One of the most frequently performed operations is the laparoscopic proximal …

bariatric surgery
bypass surgery
type 2 diabetes mellitus
  • 25 Jan, 2021
  • 1 location
The Effect of Lifestyle Treatment in Patients With Morbid Obesity (LIFETIME)

The effect of lifestyle treatment on physical capacity, maximal strength, eating behavior and quality of life in patients with morbid obesity (LIFETIME)

Accepts healthy volunteers
  • 05 Mar, 2022
  • 3 locations
Bariatric Surgery for the Reduction of cArdioVascular Events Randomized Controlled Trial (BRAVE)

The primary objective of this study is to evaluate if, in patients with severe obesity (body mass index (BMI) ≥35 kg/m2) and high-risk cardiovascular disease (CVD), bariatric surgery compared to

  • 07 Oct, 2022
  • 1 location