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Found 906 clinical trials
Efficacy and Safety of Peropirone Hydrochloride Tablets in the Treatment of Adolescent Bipolar Disorder Depression

Bipolar disorder, a type of mood disorder that occurs in various forms, such as depression, mania, hypomania or irregularity.According to the World Health Organization mental health survey, the

  • 0 views
  • 10 Apr, 2021
  • 1 location
Osteoporosis Treatment in Post-menopausal Women

The study will be conducted to assess the depressive symptoms and related markers in the postmenopausal female after anti-osteoporosis treatment.

  • 0 views
  • 22 Jan, 2021
  • 2 locations
Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy

Major depression is a highly prevalent, chronic, and debilitating mental health problem with significant social cost that poses a tremendous economic burden. Winter seasonal affective disorder

depressive symptoms
depression
phototherapy
behavioral therapy
antidepressants
  • 224 views
  • 22 Jan, 2021
  • 1 location
Stepped Care aiTBS 2 Depression Study (Ghent)

Antidepressant-free unipolar melancholic depressed patients (at least stage 2 treatment-resistant) will be selected by a certified psychiatrist, who will administer (semi-)structured clinical interviews. Because concomitant antidepressant treatment can confound outcome results, all patients will go through a medication washout before entering the study and they will be free from any …

antipsychotics
antidepressants
benzodiazepines
selective serotonin reuptake inhibitors
depressed
  • 2 views
  • 21 Jan, 2021
  • 1 location
Home-administered tDCS for Treatment of Depression

This study will determine the safety and efficacy of home administered tDCS in adults with unipolar depression. The device used to administer tDCS will be the Soterix Medical 1X1 mini-CT. 32 tDCS sessions of 30 minutes each will be delivered over 10 weeks.

  • 0 views
  • 13 Mar, 2021
  • 1 location
Personalized rTMS for Resistant Depression

The investigators hypothesize that personalizing the rTMS targets using functional MRI will increase its efficacy. The most dysfunctional regions or the most dysfunctional network will be stimulated homogeneously. Individualized rTMS will be compared to traditional rTMS procedure and to trans-cranial direct current stimulation (tDCS) in a randomized cross-over trial. In …

transcranial magnetic stimulation
depression
major depressive disorder
depressed mood
antidepressants
  • 32 views
  • 25 Jan, 2021
  • 2 locations
Mechanisms of Rumination Change in Adolescent Depression

This study will evaluate whether a newer treatment, rumination-focused cognitive behavioral treatment, which includes mindfulness and can be used to reduce ruminative habits, change ways in which key brain regions interact with each other (e.g.., often called connectivity), and whether these changes in habits and brain connectivity can reduce the …

behavioral therapy
depressive disorder
remission
behavior modification
major depressive disorder
  • 7 views
  • 23 Jan, 2021
  • 1 location
Technology Enhanced Family Treatment

The investigators propose to enhance the scalability of family-focused therapy (FFT), a 12-session evidence-based therapy for youth at high risk for mood disorders, through augmentation with a

  • 0 views
  • 22 Jan, 2021
  • 1 location
Effect of Systemic Inflammation on Emotion and Cognition in Patients With Mood Disorder - A Vaccine Study

The purpose of this pilot study is to investigate and compare the effect of a mild inflammatory stimulus (typhoid vaccine) on immune response, mood and cognition in healthy volunteers compared to patients with history Major Depressive Disorder (MDD) (not currently depressed and no symptoms of depression in the past 6 …

depressive symptoms
major depressive disorder
depressed mood
depression
antidepressants
  • 81 views
  • 24 Jan, 2021
  • 1 location
Theta-Burst Stimulation in Major Depressive Episodes With Mixed Characteristics.

The investigators will perform a double-blind, randomized, sham-controlled clinical trial of theta-burst stimulation (TBS) in mixed depressive episodes of both bipolar and major depressive disorders. Will be selected 90 patients aged 18-65 years with diagnosis of TB (I or II) or MDD in moderate or severe major depressive episode with …

  • 0 views
  • 23 Jan, 2021
  • 1 location