Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 906 clinical trials
Anti-inflmmation Treatment in Mood Disorder and Deep Learning Prediction Model

This three-year study will enroll 180 patients with mood disorders (90 patients with major depressive disorder and 90 patients with bipolar disorder) and high pro-inflammatory cytokine levels

  • 0 views
  • 27 Jan, 2021
  • 1 location
A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth

This study consists of a 6-week, open-label, randomized clinical trial study to compare efficacy and tolerability of the natural treatments omega-3 fatty acids, inositol, and N-acetylcysteine (NAC) in the treatment of mood dysregulation in children and adolescents (ages 5-17). Subjects will be randomized to one of two arms: 1) omega-3 …

depression
omega-3 fatty acids
anxiety
depressed mood
  • 17 views
  • 25 Jan, 2021
  • 1 location
Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)

Background Electroconvulsive therapy (ECT) is used to treat people with severe depression. During ECT, the brain is given electric pulses that cause a seizure. Although it is effective, it can cause side effects, including memory loss. Researchers want to study a new way to give ECT called iLAST. Objective To …

depression
electroconvulsive therapy
depressed mood
severe depression
anesthesia
  • 6 views
  • 21 Apr, 2021
  • 1 location
Telephone-administered Relapse Prevention for Depression

This study determines the effectiveness of telephone-delivered cognitive-behavioral continuation therapy (T-CT) in comparison to usual care in people with recurrent or chronic depression. The primary research question is whether participating in T-CT reduces depressive relapses. The continuation therapy comprises eight therapy sessions delivered over the telephone by a trained therapist …

depressive symptoms
remission
major depressive disorder
psychiatric disorder
psychotherapy
  • 31 views
  • 18 Feb, 2021
  • 23 locations
An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression

The purpose of this study is to evaluate the effectiveness of two adaptive treatment strategies (ATSs) for adolescent depression. The ATSs include delivery of an evidence-based psychotherapy (interpersonal psychotherapy for depressed adolescents, IPT-A), systematic symptom monitoring, and an empirically-derived algorithm that specifies whether, when, and how to augment IPT-A. Two …

depressive symptoms
sertraline
major depressive disorder
psychotherapy
depression
  • 109 views
  • 26 Jan, 2021
  • 1 location
Depressed Mood Improvement Through Nicotine Dosing 2

Deficits in cognitive control are core features of late-life depression, contributing both to emotion dysregulation and problems with inhibiting irrelevant information, conflict detection, and working memory. Clinically characterized as executive dysfunction, these deficits are associated with poor response to antidepressants and higher levels of disability. Improvement of cognitive control network …

  • 0 views
  • 03 Feb, 2021
  • 1 location
Repetitive Transcranial Magnetic Stimulation Trajectory of Outcomes Study

This prospective, single-arm, open-label feasibility study will assess the safety, tolerability, and effectiveness of repetitive transcranial magnetic stimulation (rTMS) in patients with major depression (MDD) to test the hypothesis that remission rates can be increased by additional treatment sessions.

depression
remission
transcranial magnetic stimulation
depressed mood
psychotropic drugs
  • 0 views
  • 27 Jan, 2021
  • 1 location
A Multi-component Intervention to Improve Medication Adherence in People With Depressive Disorders

Objective: The study of medication adherence in depression (MAPDep study) aims to evaluate the effectiveness and cost-effectiveness of a multi-component strategy to enhance patient-centered care to improve adherence toward medications in patients with depression, formed by an educational intervention to psychiatrists and/or a collaborative care intervention group to patients and …

depressive symptoms
depression
depressed mood
emotional distress
major depressive disorder
  • 0 views
  • 24 Jan, 2021
  • 2 locations
Cerebral Neuroinflammation During Major Depressive Episode

the investigators make the following assumptions: 1) neuroinflammation in MDD can be measured by the [18 F ] DPA- 714 ; 2) it is accompanied by anatomical and functional changes in the frontal subcortical loops, strongly involved in MDD ; 3) neuroinflammation in patients might be a biomarker related to …

remission
antidepressants
blood tests
depressive episode
major depressive disorder
  • 7 views
  • 25 Jan, 2021
  • 2 locations
A 12-weeks Study to Evaluate Sulforaphane in the Treatment of Depression

Major depressive disorder is a serious, recurrent and disabling mental disorder, which is the second leading cause of years lost to disability worldwide. Accumulating evidence suggests the important role for inflammation and oxidative stress in the pathophysiology of depression. Sulforaphane extracted from broccoli sprout is an agent with potent anti-oxidant …

psychiatric disorder
depression
selective serotonin reuptake inhibitors
antidepressants
depressed mood
  • 0 views
  • 25 Jan, 2021
  • 1 location