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Found 7 clinical trials
  • 0 views
  • 26 May, 2022
  • 1 location
A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Montanide ISA 51 before it is given. Montanide ISA 51 is an ingredient that helps create a stronger immune response in people, which helps the vaccine work better. This study has two phases: Priming

montanide isa-51
cancer
sargramostim
tumor cells
diffuse intrinsic pontine glioma
  • 0 views
  • 07 Oct, 2022
  • 4 locations
Vaccination With 6MHP, With or Without Systemic CDX-1127, in Patients With Stage II-IV Melanoma (Mel-65)

boost immune responses to the vaccine. In this study, the adjuvants are Montanide ISA-51 and polyICLC. The investigators will monitor these effects by performing tests in the laboratory on participants

peptide vaccine
immunologic adjuvant
malignant melanoma of skin
brain metastases
vaccination
  • 13 views
  • 17 May, 2022
  • 2 locations
CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer

This phase I/II trial studies the best dose and side effects of recombinant human EGF-rP64K/montanide ISA 51 vaccine (CIMAvax) and nivolumab and to see how well they work in treating patients

liver metastases
direct bilirubin
recombinant human egf-rp64k/montanide isa 51 vaccine
pembrolizumab
cancer treatment
  • 34 views
  • 04 Oct, 2022
  • 5 locations
A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence

This early phase I trial studies the side effects of a vaccine called CIMAvax-EGF and to see how well it works in preventing lung cancer from developing in patients at high risk for lung cancer or coming back (recurrence) in stage IB-IIIA non-small cell lung cancer survivors. In many cancers …

pneumonia
pulmonary function test
cancer
chronic obstructive pulmonary disease
immunomodulator
  • 1 views
  • 21 Apr, 2022
  • 1 location
PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma (PRiME)

The primary goal of this prospective clinical trial is to evaluate the safety of PEP-CMV in patients with recurrent medulloblastoma and malignant glioma. Patients with histologically-proven medulloblastoma or malignant glioma who had received prior therapy for their initial diagnosis and subsequently had tumor recurrence/progression may be enrolled any time after …

x-rays
montanide isa-51
cancer
malignant glioma
MRI
  • 22 views
  • 19 Jun, 2022
  • 1 location
Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors

This phase I trial studies the side effects of survivin long peptide vaccine and how it works with the immune system in treating patients with neuroendocrine tumors that have spread to other parts of the body (metastatic). Tumor cells make proteins that are not usually produced by normal cells. The …

  • 12 views
  • 04 Oct, 2022
  • 1 location