Found 135 clinical trials
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Neurology
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Currently Recruiting
Chemotherapy For Metastatic Grade 3 Poorly Differentiated NEuroendocrine Carcinoma Of GastroEnteroPancreatic And Unknown Primary
there is a need for improving chemotherapy regimen for metastatic G3 NEC of GEP and Unknown origin and this goal may be achieved through more "personalized" chemotherapy regimen.the hypothesis is that mFOLFIRINOX regimen could be a good candidate for challenging the platinum-etoposide regimen in patients with metastatic G3 NEC of …
- 0 views
- 27 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Feasibility and Effectiveness of a Personalized Inpatient Program for Persistent Depressive Disorder
The major objective of this study is to evaluate a new conceptualized personalized concept of Cognitive Behavioral Analysis System of Psychotherapy (CBASPersonalized) in the treatment of patients with persistent depressive disorder (PDD), childhood maltreatment and a high rate of comorbidity. Patients receive a two-phase-treatment-program (six-weeks inpatient-treatment and six-to-twelve-weeks blended-online-aftercare) in …
- 0 views
- 26 Jan, 2021
- 2 locations
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Sweet Tooth: Nature or Nurture? Role of Long-term Dietary Sweetness Exposure on Sweetness Preferences
In recent years, social pressure has been exerted towards lowering sugar and sweetness levels in foods, with the aim of decreasing the sweetness preference of the general population. However, the resilience/flexibility of sweetness preferences and the impact on energy intake is a fundamental knowledge gap. Recent, relatively long-term studies limited …
- 0 views
- 01 Feb, 2021
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Oncology
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Currently Recruiting
Rituximab and Lenalidomide vs Rituximab Alone as Maintenance After R-chemoterapy for Relapsed/Refractory FL Patients
A randomized phase III multicenter trial assessing efficacy and toxicity of a combination of Rituximab and Lenalidomide (R2) vs Rituximab alone as maintenance after chemoimmunotherapy with Rituximab-chemotherapy (R-CHT) for relapsed/refractory FL patients not eligible for autologous transplantation (ASCT)
- 37 views
- 24 Jan, 2021
- 36 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
A Randomized Comparison of CLOpidogrel Monotherapy Versus Extended Dual-antiplatelet Therapy Beyond 12 Months After Implantation of Drug-eluting StEnts in High-risk Lesions or Patients; A-CLOSE Trial
The investigators hypothesized that clopidogrel mono-therapy will not be inferior to the extended DAPT in terms of the occurrence of both ischemic and bleeding events, for lesions or patients at
- 0 views
- 23 Jan, 2021
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Immunology
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Currently Recruiting
Supporting Treatment Outcomes Among PWID
suppression) in HCV mono- and HIV/HCV co-infected PWID can be optimized by tailoring treatment support in 7 PWID-focused integrated HIV/HCV prevention and treatment centers in India.
- 0 views
- 27 Jan, 2021
- 1 location
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Multi-country trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Switch to Oral Antibiotics in Gram-negative Bacteremia
Eligible subjects will be those age 18 years or more with mono-microbial blood stream infection caused by E. coli, Klebsiella species, Enterobacter species, Serratia species, Citrobacter species
- 73 views
- 10 Feb, 2021
- 9 locations
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM
18 years and are currently taking metformin, insulin or both drugs (DINAMO TM) or who are treatment nave or not on active treatment after metformin withdrawal (DINAMO TM MONO) .
- 106 views
- 01 Mar, 2021
- 249 locations
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Phase 4 trial
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Accepting pediatric ages
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Accepting Seniors
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1000s of participants
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An interventional trial
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For all genders
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Immunology
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Currently Recruiting
Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK)
To Identify the collected cases who can stop NAs safely with satisfactory clinical outcome including sustain viral remission and HBsAg clearance among chronic hepatitis B(CHB) patients.
- 0 views
- 01 Mar, 2021
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Neurology
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Currently Recruiting
Enhancing the Clinical Effectiveness of Depression Screening Using Patient-targeted Feedback in General Practices
The multi-center GET.FEEDBACK.GP randomized controlled trial is designed based on patients' needs and preferences. In order to evaluate the effect of feedback in the broader setting of primary care, a total of 1076 primary care patients with elevated levels of depression (PHQ-9 score 10) will be randomized into three groups …
- 0 views
- 27 Jan, 2021
- 2 locations