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Found 135 clinical trials
Chemotherapy For Metastatic Grade 3 Poorly Differentiated NEuroendocrine Carcinoma Of GastroEnteroPancreatic And Unknown Primary

there is a need for improving chemotherapy regimen for metastatic G3 NEC of GEP and Unknown origin and this goal may be achieved through more "personalized" chemotherapy regimen.the hypothesis is that mFOLFIRINOX regimen could be a good candidate for challenging the platinum-etoposide regimen in patients with metastatic G3 NEC of …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Feasibility and Effectiveness of a Personalized Inpatient Program for Persistent Depressive Disorder

The major objective of this study is to evaluate a new conceptualized personalized concept of Cognitive Behavioral Analysis System of Psychotherapy (CBASPersonalized) in the treatment of patients with persistent depressive disorder (PDD), childhood maltreatment and a high rate of comorbidity. Patients receive a two-phase-treatment-program (six-weeks inpatient-treatment and six-to-twelve-weeks blended-online-aftercare) in …

  • 0 views
  • 26 Jan, 2021
  • 2 locations
Sweet Tooth: Nature or Nurture? Role of Long-term Dietary Sweetness Exposure on Sweetness Preferences

In recent years, social pressure has been exerted towards lowering sugar and sweetness levels in foods, with the aim of decreasing the sweetness preference of the general population. However, the resilience/flexibility of sweetness preferences and the impact on energy intake is a fundamental knowledge gap. Recent, relatively long-term studies limited …

  • 0 views
  • 01 Feb, 2021
  • 1 location
Rituximab and Lenalidomide vs Rituximab Alone as Maintenance After R-chemoterapy for Relapsed/Refractory FL Patients

A randomized phase III multicenter trial assessing efficacy and toxicity of a combination of Rituximab and Lenalidomide (R2) vs Rituximab alone as maintenance after chemoimmunotherapy with Rituximab-chemotherapy (R-CHT) for relapsed/refractory FL patients not eligible for autologous transplantation (ASCT)

platelet count
neutrophil count
bendamustine
lenalidomide
rituximab
  • 37 views
  • 24 Jan, 2021
  • 36 locations
A Randomized Comparison of CLOpidogrel Monotherapy Versus Extended Dual-antiplatelet Therapy Beyond 12 Months After Implantation of Drug-eluting StEnts in High-risk Lesions or Patients; A-CLOSE Trial

The investigators hypothesized that clopidogrel mono-therapy will not be inferior to the extended DAPT in terms of the occurrence of both ischemic and bleeding events, for lesions or patients at

  • 0 views
  • 23 Jan, 2021
Supporting Treatment Outcomes Among PWID

suppression) in HCV mono- and HIV/HCV co-infected PWID can be optimized by tailoring treatment support in 7 PWID-focused integrated HIV/HCV prevention and treatment centers in India.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Switch to Oral Antibiotics in Gram-negative Bacteremia

Eligible subjects will be those age 18 years or more with mono-microbial blood stream infection caused by E. coli, Klebsiella species, Enterobacter species, Serratia species, Citrobacter species

  • 73 views
  • 10 Feb, 2021
  • 9 locations
Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

18 years and are currently taking metformin, insulin or both drugs (DINAMO TM) or who are treatment nave or not on active treatment after metformin withdrawal (DINAMO TM MONO) .

metformin
c-peptide
empagliflozin
fasting
linagliptin
  • 106 views
  • 01 Mar, 2021
  • 249 locations
Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK)

To Identify the collected cases who can stop NAs safely with satisfactory clinical outcome including sustain viral remission and HBsAg clearance among chronic hepatitis B(CHB) patients.

hepatitis b antigen
chronic hepatitis
hepatitis b e antigen
hepatitis
  • 0 views
  • 01 Mar, 2021
Enhancing the Clinical Effectiveness of Depression Screening Using Patient-targeted Feedback in General Practices

The multi-center GET.FEEDBACK.GP randomized controlled trial is designed based on patients' needs and preferences. In order to evaluate the effect of feedback in the broader setting of primary care, a total of 1076 primary care patients with elevated levels of depression (PHQ-9 score 10) will be randomized into three groups …

depressed mood
depression screening
  • 0 views
  • 27 Jan, 2021
  • 2 locations