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Found 135 clinical trials
Combined Optokinetic Stimulation and Cueing-based Reading Therapy to Treat Hemispatial Neglect Following Stroke

patients. It will be a mono-centric, randomized, controlled, clinical trial. Using a crossover design with two arms, patients will either receive the intervention therapy (OKS-READ) first and subsequently

  • 0 views
  • 24 Jan, 2021
  • 1 location
Active Knee Prosthesis Study for Improvement of Locomotion for Above Knee Amputees

antagonistic muscle anatomy of the human knee joint. This device mimics the synergistic muscle activity at the knee using a double series-elastic actuator (SEA) system that resembles the major mono

agonist-antagonist
prosthetic knee
  • 2 views
  • 07 Nov, 2020
  • 2 locations
Phase III Trial of Gemcitabine Curcumin and Celebrex in Patients With Advance or Inoperable Pancreatic Cancer

improvement in a therapy’s safety and efficacy over mono-therapeutic regiments, especially if the combined drugs differ in their mode of action. In a recent paper that was accepted for publication

adenocarcinoma
oxaliplatin
platelet count
metastatic pancreatic cancer
fluorouracil
  • 156 views
  • 07 Nov, 2020
  • 1 location
Different Approaches to Thoracic Paravertebral Block

Thoracic paravertebral block (TPB) in thoracic surgery is practiced since the development of minimally invasive surgery. Historically, thoracic epidural analgesia is done in open thoracic surgery. Thoracotomy with rib spacing causes strong post-operative pain that is well controlled with epidural analgesia and allows less use of morphine. However, this method …

analgesia
paravertebral block
thoracic surgery
morphine
  • 0 views
  • 27 Jan, 2021
  • 1 location
Tenofovir Alafenamide With Fine Needle Aspiration Biopsy in Chronic Hepatitis B:

The objective of this study is to identify immunological mechanisms that contribute to normalization of liver inflammation in chronic hepatitis B (CHB) patients starting the antiviral nucleoside analogue, Tenofovir alafenamide (TAF).

  • 0 views
  • 23 Jan, 2021
  • 1 location
Multispectral Imaging Endoscopy in Digestive Inflammation

The study aims as principal objective to show the association between reflectance intensity of mucosa at different wave lengths and the presence of acute or chronic inflammation in stomach or rectum and normal mucosa; the presence of glandular atrophy in stomach or intestinal metaplasia. The secondary objectives are: to identify …

  • 0 views
  • 18 Feb, 2021
  • 1 location
PDE6A Gene Therapy for Retinitis Pigmentosa

The PDE6A gene encodes a subunit of the rod phosphodiesterase. The loss of this enzyme function leads to a chronically elevated cGMP level which causes an increased calcium inflow into the cell and thereby the hyperactivation of cell death pathways. The goal of the PIGMENT study is to develop, produce …

gene therapy
other disease
  • 0 views
  • 26 Jan, 2021
  • 1 location
Exercise Training in Pediatric-Onset Multiple Sclerosis Patients

Multiple sclerosis is one of the leading causes of disability in young adults. It is known that patients with pediatric onset multiple sclerosis (POMS) experience their first demyelinating attack before the age of 18. However, studies conducted with individuals with pediatric onset of multiple sclerosis have been reported to be …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial)

The main objective of this trial is to explore the activity of chlorambucil, an alkylating agent commonly used in chronic lymphocytic leukemia treatment, in metastatic patients, gBRCA, including VUS, or DDR mutated, previously treated with a platinum-containing chemotherapy.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Lactobacillus Reuteri in the Supportive Therapy of Periodontitis

Literature shows the potential effectiveness of L. reuteri as an adjunct to non-surgical periodontal therapy in initial treatment of periodontitis, but also underlines the limits of the conclusions, and the heterogeneity and limited sample size of the available studies. Therefore, there is a need for longer-term, randomized, controlled studies. Moreover, …

  • 0 views
  • 26 Jan, 2021
  • 1 location