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Found 2 clinical trials
A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Patients (MOMENTUM)

MOMENTUM is a randomized, double-blind, active control Phase 3 trial intended to confirm the differentiated clinical benefits of the investigational drug momelotinib (MMB) versus danazol (DAN

polycythemia
extramedullary hematopoiesis
conjugated bilirubin
direct bilirubin
myelofibrosis
  • 249 views
  • 13 Apr, 2021
  • 232 locations
A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis Post Polycythemia Vera Myelofibrosis or Post-Essential Thrombocythemia Myelofibrosis

This study (study ID PAC203 North America; PAC303 ex-North America) is evaluating 200 mg BID of pacritinib compared to physician's choice (P/C) therapy in patients with MF and severe thrombocytopenia (platelet count <50,000/L). Approximately 348 patients in total will be enrolled, randomized 2:1 to either pacritinib (approximately 232 patients) or …

polycythemia
renal function
conjugated bilirubin
pacritinib
ejection fraction
  • 506 views
  • 09 May, 2021
  • 176 locations