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Found 2 clinical trials
Intraperitoneal Paclitaxel Plus Systemic mFOLFOX6 (IPLUS)

Treatment for stage 4 gastric cancer with peritoneal carcinomatosis has been unchanged for decades. The median survival for stage 4 gastric cancer is 9-14 months with systemic chemotherapy. Intraperitoneal chemotherapy in combination with systemic chemotherapy is under many clinical trials mainly in Japan, and are showing promising results. This is …

platelet count
paclitaxel
intraperitoneal chemotherapy
adenocarcinoma
neutrophil count
  • 16 views
  • 12 Feb, 2022
  • 1 location
Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer (DUREC)

The addition of durvalumab to total neoadjuvant therapy (TNT) in locally advanced rectal cancer may improve the pathological complete response rate. The induction platinum-based chemotherapy may increase the neoantigen formation together with the chemoradiotherapy period. Starting durvalumab during the first chemotherapy session and continuing during the 6-week period of chemoradiotherapy …

chemoradiotherapy
capecitabine
oxaliplatin
adenocarcinoma
fluorouracil
  • 37 views
  • 28 Feb, 2022
  • 2 locations