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Found 3 clinical trials
Testing the Combination of MLN4924 (Pevonedistat) Carboplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy

This phase II trial studies how well MLN4924 (pevonedistat), carboplatin, and paclitaxel work in treating patients with stage IIIB or IV non-small cell lung cancer. Pevonedistat may stop the

measurable disease
platinum-based chemotherapy
pevonedistat
chemotherapy drugs
carboplatin
  • 1 views
  • 09 May, 2021
  • 4 locations
Ixazomib and Pevonedistat in Treating Patients With Multiple Myeloma That Has Come Back or Does Not Respond to Treatment

This IB trial studies side effects and best dose of pevonedistat when given together with ixazomib in treating patients with multiple myeloma that has come back or does not respond to treatment. Pevonedistat and ixazomib may stop the growth of tumor cells by blocking some of the enzymes needed for …

measurable disease
proteasome inhibitor
line of therapy
gilbert's syndrome
immunomodulatory imide drug
  • 1 views
  • 07 May, 2021
  • 6 locations
Pevonedistat and Belinostat in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

This phase I trial studies side effects and best dose of pevonedistat and belinostat in treating patients with acute myeloid leukemia or myelodysplastic syndrome that has come back (relapsed) or does not respond to treatment (refractory). Drugs used in chemotherapy, such as pevonedistat and belinostat, work in different ways to …

  • 0 views
  • 21 Apr, 2021
  • 1 location