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Found 26 clinical trials
Transcatheter Mitral Valve InterventiOn Single Center Registry in CHinese Patients With Mitral Valve Disease (TORCH-M)

The purpose of this study is to evaluate the safety and effectiveness of transcatheter mitral valve intervention in Chinese population with mitral valve disease.

  • 15 Jul, 2021
  • 1 location
Prospective Multicenter Study on Mitral Annular Disjunction

Observational cohort prospective multicenter study on patients with mitral annular disjunction (MAD). MAD is defined as a separation (1 mm) between the atrial wall-mitral valvular junction and the left ventricular free wall during end-systole

  • 23 Jun, 2021
  • 1 location
Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair (ReChord)

The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without

mitral valve disease
mitral valve repair
  • 26 Jan, 2022
  • 15 locations
Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial (CLASP IID/IIF)

To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair System in patients with degenerative mitral regurgitation (DMR) who have been determined to be at prohibitive risk for mitral valve surgery by the Heart Team, and in patients with functional mitral regurgitation (FMR) on guideline directed medical …

heart failure
medical therapy
mitral valve repair
functional mitral regurgitation
  • 06 May, 2022
  • 83 locations
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation (SUMMIT)

effectiveness of the Tendyne Transcatheter Mitral Valve System for the treatment of patients with symptomatic, moderate-to-severe or severe mitral regurgitation or for patients with symptomatic mitral valve

mitral valve replacement
mitral valve disease
mitral valve repair
mitral annular calcification
  • 27 Jun, 2022
  • 76 locations
Bi-atrial Versus Left Atrial Ablation for Patients With Rheumatic Mitral Valve Disease and Non-paroxysmal Atrial Fibrillation

This study is aimed to compare the efficacy of bi-atrial ablation with left atrial ablation for atrial fibrillation during mitral valve surgery in patients with rheumatic mitral valve disease

  • 26 May, 2022
Frailty in Elderly Patients Receiving Surgical or Percutaneous Procedures for Valvular Disorders (FRASER-VD)

In Italy, life expectancy at birth has reached 80 years in men and 85 in women; in about 50 years, life expectancy at the age of 80 has increased by an extraordinary 61% and 55%, respectively, due to more effective therapies and lower mortality of many diseases. Yet, chronic diseases …

aortic valve disease
chronic diseases
aortic valve stenosis
aortic stenosis
  • 30 Jan, 2022
  • 1 location
The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves). (MITRAL-II)

A prospective multicenter study enrolling high surgical risk patients with severe mitral annular calcification (MAC) and symptomatic mitral valve disease. There are 2 arms in this study

mitral valve disease
  • 01 Jul, 2022
  • 7 locations
AHEAD: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System (AHEAD)

This study will evaluate the safety of the Cardiovalve Transfemoral Mitral Valve System with its associated procedure, and observe the device performance in reducing mitral regurgitation. Data collected in this clinical study will include 30-day safety and performance, and long-term clinical outcomes over a follow-up of 2 years.

heart failure
constrictive pericarditis
coronary artery disease
  • 03 Mar, 2022
  • 7 locations
Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery (PREFER-CABG)

This study evaluates the efficacy and safety of single dose preoperative ferric carboxymaltose in the prevention of postoperative infections and blood transfusions in patients scheduled for cardiac surgery. Half of the patients will receive ferric carboxymaltose and half of the patients physiological saline solution as placebo.

aortic valve disease
mitral valve disease
heart disease
coronary artery stenosis
  • 15 Feb, 2022
  • 1 location