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Found 9 clinical trials
Featured trial
A Study to Evaluate the Efficacy, Safety and Tolerability of Combinations Study medication and Mirabegron Compared to Study medication and Mirabegron Monotherapy in the Treatment of Overactive Bladder

A Study to Evaluate the Efficacy, Safety and Tolerability of Combinations Study medication and Mirabegron Compared to Study medication and Mirabegron Monotherapy in the Treatment of Overactive

  • 180 views
  • 23 Nov, 2020
  • 1 location
Featured trial
SYNERGY

SYNERGY

  • 99 views
  • 08 Nov, 2020
  • 1 location
Sequencing and Combination of Mirabegron and TTNS in Overactive Bladder Syndrome: a Multicenter, Randomized, Open-label, Crossover Trial

Research question: A wealth of existing research has established the independent effectiveness of mirabegron and neuromodulation in the treatment of overactive bladder syndrome

  • 0 views
  • 22 Mar, 2022
  • 1 location
A Phase 3, Double-blind, Randomized, Multicenter, Parallel Group, Placebo-controlled Sequential Dose Titration Study to Evaluate Efficacy, Safety and Pharmacokinetics of Mirabegron in Pediatric Subjects From 5 to < 18 Years of Age With Overactive Bladder (Dolphin)

The purpose of this study is to evaluate the efficacy of mirabegron in children (5 to < 12 years of age) with OAB. This study will also evaluate the safety and tolerability of

incontinence
mirabegron
  • 9 views
  • 14 Sep, 2022
  • 27 locations
Activation of Brown Adipose Tissue Metabolism Using Mirabegron (GB9)

receptor (ADBR3) at higher doses of Mirabegron may be required to elicit changes in glycemia, but should be combined with Beta-1 adrenergic receptor (ADRB1) antagonists to suppress the unwanted effects on

glucose tolerance test
oral glucose tolerance test
Accepts healthy volunteers
  • 0 views
  • 29 May, 2022
  • 1 location
The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics

The investigator hypothesizes that treatment with the ß3 agonist mirabegron results in improved glucose metabolism, including a reversal of prediabetes in obese, insulin-resistant human research

hemoglobin a1c
body mass index
insulin
Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
Posterior Tibial Nerve Stimulation (PTNS) Plus Mirabegron to Treat Refractory OAB Symptoms (PTNS-M Study)

stimulation (PTNS) and mirabegron treatment versus PTNS with placebo on change in the number of UUI episodes over a 12-week treatment course. Secondary aims include comparing the efficacy of combined

incontinence
percutaneous tibial nerve stimulation
mirabegron
Accepts healthy volunteers
  • 0 views
  • 15 Dec, 2021
  • 1 location
Mechanisms for Activation of Beige Adipose Tissue in Humans

Mirabegron (Myrbetriq®, Astellas) is a highly specific and well-tolerated ß3 agonist marketed for overactive bladder. This trial will assess the effects of mirabegron on glucose tolerance and

impaired glucose tolerance
fasting
Accepts healthy volunteers
  • 283 views
  • 24 Mar, 2022
  • 1 location
The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic Rate

: to better understand the effects of mirabegron, a beta-3 adrenergic receptor agonist, on brown fat activity. Eligibility Healthy, lean adult

blood test
Accepts healthy volunteers
  • 321 views
  • 21 Sep, 2022
  • 1 location