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Found 27 clinical trials
Rescue Therapy for Helicobacter Pylori Eradication

of the minocycline and metronidazole based bismuth quadruple therapy in the rescue treatment of helicobacter pylori infection.

potassium citrate
bismuth
citric acid
metronidazole
tetracycline
  • 0 views
  • 02 Apr, 2021
  • 1 location
Neuroimmune Dysfunction in Alcohol Use Disorder

The objective of this proposal is to advance medication development for alcohol use disorder by examining the efficacy and mechanisms of action of minocycline, a neuroimmune modulator, as a

heavy drinking
minocycline
alcohol use disorder
  • 45 views
  • 20 Mar, 2021
  • 1 location
Intra-Arterial Neuroprotective Agents and Cold Saline in Ischemic Stroke Intervention

endovascular reperfusion would provide immediate, targeted therapy directly to the damaged brain territory. Hypothermia, minocycline and magnesium can target multiple facets of the complex ischemic injury

  • 0 views
  • 10 Sep, 2021
  • 1 location
Mino-Lok Therapy (MLT) for the Treatment of CRBSI/CLABSI

This is a Phase 3, multi-center, randomized, open-label, assess-blind study to determine the efficacy and safety of MLT, a novel antibiotic lock therapy that combines minocycline with edetate

bloodstream infection
antibiotic lock therapy
venipuncture
fever
minocycline
  • 67 views
  • 11 Jul, 2021
  • 34 locations
A Companion Treatment Study for Patients With Moderate to Severe Acne Vulgaris

Acne vulgaris is a common disease of both males and females, usually manifesting initially during adolescence. The use of retinoic acid analogues such as adapalene, tazarotene and isotretinoin are also commonly prescribed to treat inflammation; dysregulated sebum production and comedonal acne. This study seeks to evaluate the efficacy and safety …

  • 0 views
  • 11 Jul, 2021
  • 2 locations
STaph Aureus Resistance-Treat Early and Repeat (STAR-TER)

To evaluate the micro-biologic efficacy and safety of a streamlined treatment for early onset methicillin-resistant staphylococcus aureus (MRSA) in patients with cystic fibrosis.

nasal potential difference
pilocarpine
isoproterenol
staphylococcus aureus
fibrosis
  • 22 views
  • 24 Jan, 2021
  • 8 locations
The Role of Gut Microbiota in Hypertension

hypothesize that gut microbiota is involved in the neuroinflammation-mediated initiation and establishment of RH, and targeting gut microbiota by minocycline would produce beneficial outcomes in RH.

stroke
cardiovascular disease
hypertensive medication
systolic blood pressure
uncontrolled hypertension
  • 80 views
  • 13 Feb, 2021
  • 1 location