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Found 27 clinical trials
Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections.

The number of cardiac implantable electronic devices (CIEDs) implanted each year has grown rapidly over the past two decades. CIED infections, defined as infections involving the generator implant site (pocket) and/or intravascular leads, have become increasingly prevalent, with the rate of growth in infections outpacing that of CIED procedures. The …

clindamycin
corticosteroids
  • 0 views
  • 22 Aug, 2021
  • 1 location
Minocycline Treatment in Retinitis Pigmentosa

The aim of this study is to evaluate the efficacy and safety of oral minocycline (100mg/d), administered for 6 months, for the treatment of patients with retinitis pigments(RP).

retinitis
electroretinogram
blindness
flashes
minocycline
  • 268 views
  • 24 Jan, 2021
  • 1 location
Minocycline in MS: Confirmation of Benefit

with minocycline until the endpoint is reached or to a maximum of 24 months or until the last-enrolled participant reaches their 12 month visit.

MRI
oligoclonal bands
disease or disorder
demyelination
brain mri
  • 10 views
  • 23 Jan, 2021
  • 1 location
Minocycline Augmentation of Clozapine for Treatment Resistant Schizophrenia

This a randomized double-blind placebo controlled trial which aims to determine the beneficial effects of minocycline augmentation to clozapine in partial responders to Treatment Resistant

clozapine
schizophrenia
antipsychotics
  • 43 views
  • 23 Jan, 2021
  • 4 locations
Effect of Minocycline on Delirium Incidence in Critically Ill Patients

are at higher risk for the development of delirium. Several studies suggest that minocycline, through its anti-inflammatory effect, was able to prevent neuronal dysfunction in different models of ICU

coma
critical illness
minocycline
mechanical ventilation
bdnf
  • 1 views
  • 19 Sep, 2021
  • 2 locations
Study 1: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients

perhaps eventually cure neurogenic hypertension (NH). This study is designed to evaluate a low and high dose of minocycline to test the hypothesis that minocycline treatment would produce antihypertensive

systolic blood pressure
metabolic syndrome
antihypertensive drugs
cardiovascular disease
diuretics
  • 41 views
  • 04 Jul, 2021
  • 1 location
Scaling and Root Planing (SRP) With and Without Minocycline HCl Microspheres 1 mg

The primary goal of this study is to investigate the qualitative and quantitative effects of scaling and root planing (SRP) with and without minocycline HCL microspheres, 1 mg on periodontal

  • 1 views
  • 15 Sep, 2021
  • 1 location
A Pilot Study Investigating the Efficacy of Minocycline and N-Acetyl Cysteine for Bipolar Depression

The purpose of the Pilot Study Investigating the Efficacy of Minocycline and n-acetylcysteine for Bipolar Depression is to test the effectiveness of minocycline, n-acetylcysteine, and combined

minocycline
depression
mood stabilizer
n-acetylcysteine
lithium
  • 88 views
  • 20 May, 2021
  • 1 location
Safety and Efficacy Comparison of Minocycline Microgranules Versus Lymecycline in the Treatment of Mild to Moderate Acne

This is a clinical trial to compare the benefits and possible adverse events of two antibiotic treatments for mild to moderate acne. It is expected that minocycline microgranules will be

  • 58 views
  • 08 Nov, 2020
  • 1 location
Evaluating the Role of Neuroinflammation in Low Back Pain

In this research, the study team will use brain imaging to evaluate the presence of neuroinflammation in the brains and spinal cords of patients with low back pain. The efficacy of minocycline

brain imaging
back pain
acute back pain
low back pain
  • 348 views
  • 19 Sep, 2021
  • 1 location