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Found 27 clinical trials
Intrapleural Minocycline After Aspiration of Spontaneous Pneumothorax

air leaks and reduce the rates of recurrent spontaneous pneumothorax in surgical and non-surgical patients. Many chemical irritants (tetracycline, talc, and minocycline) have been used to

tetracycline
thoracoscopy
cavity
aspiration
pleurodesis
  • 3 views
  • 07 Nov, 2020
  • 1 location
Minocycline as Adjunctive Treatment for Treatment Resistant Depression

some patients with MDD including those with TRD, display brain inflammation. Thus, patients with TRD may benefit from medications that can reduce this inflammation. Minocycline is an antibiotic which

depressive symptoms
antibiotic
citalopram
psychosis
duloxetine
  • 0 views
  • 24 Jan, 2021
  • 1 location
Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax

To test if additional minocycline pleurodesis after thoracoscopic procedures can reduce the rates of ipsilateral recurrence for patients with primary spontaneous pneumothorax.

pleurodesis
minocycline
vats
spontaneous pneumothorax
hemopneumothorax
  • 0 views
  • 07 Nov, 2020
  • 1 location
Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax

abrasion with minocycline instillation is an easy and convinent method of pleurodesis which decreases the rate of recurrence without affecting pulmonary function. In this study, we hypothesized

bullae
thoracoscopy
pleurodesis
minocycline
pleurectomy
  • 1 views
  • 07 Nov, 2020
Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax

air leaks and reduce the rates of recurrent spontaneous pneumothorax in surgical and non-surgical patients. Many chemical irritants (tetracycline, talc, and minocycline) have been used to

tetracycline
thoracoscopy
dyspnea
aspiration
pleurodesis
  • 2 views
  • 07 Nov, 2020
Neuroinflammation in Hypertension Study

To demonstrate that in patients with resistant hypertension oral treatment with minocycline via inhibition of central immune cell activation and inflammation results in reduced central

  • 0 views
  • 27 Mar, 2021
  • 1 location
Ocular Screening in Children and Young Adults at Risk for Increased Intracranial Pressure

The purpose of this study is to evaluate the vision and posterior segment of eyes in children and young adults less than 22 years of age with risk, suspicion, or past medical history significant for elevated intracranial pressure (ICP). Patients will have visual acuity and color vision tested. Assessment of …

  • 8 views
  • 26 Jan, 2021
  • 1 location
Doxycycline for Hereditary Hemorrhagic Telangiectasia

This study will investigate the effectiveness of oral doxycycline for the treatment of recurrent nasal hemorrhage in Hereditary Hemorrhagic Telangiectasia (HHT) subjects. The primary outcome for the trials will be the reduction of epistaxis severity (minutes of bleeding per week). The biological outcomes of interest are the regression of vascular …

  • 2 views
  • 25 Jan, 2021
  • 1 location
Enhanced Bioscaffold for Volumetric Muscle Loss

This is a prospective, single center study conducted at the University of Pittsburgh designed to test the applicability and utility of XenMatrix AB Surgical Graft in the restoration of function in the setting of volumetric muscle loss after soft tissue trauma.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium

clear yet and no effective therapy method was proved. According to previous study, the neuroinflammation is the main reason both for POCD and POD. Minocycline is a tetracycline derivative. Due to it's

cancer
prostatectomy
nephrectomy
  • 45 views
  • 23 Jan, 2021
  • 5 locations