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Found 61 clinical trials
Speed of Processing Training for Cognitive Deficits After Delirium in Older Adults

In this proposal, we will examine processing speed training (PST) as a potential intervention to reduce the risk of developing long-term cognitive impairment after a delirium episode.

cognitive impairment
cognitive disorder
confusion
cognitive assessment
cognitive deficits
  • 11 views
  • 23 Jan, 2021
  • 1 location
Efficacy of Oral Supplementation of Probiotics in Children With Atopic Dermatitis

Various clinical studies have evaluated the role of probiotics in children with atopic dermatitis, with some studies showing improvement in clinical outcome after supplementation of probiotics and others showing no additional benefit. This study is to provide clinical evidence of effect of a mixture of probiotics in Atopic Dermatitis (AD) …

  • 0 views
  • 29 Jan, 2021
  • 1 location
Cognition Age and RaPamycin Effectiveness - DownregulatIon of thE mTor Pathway

Evaluation of central nervous system penetration of orally administered Rapamune (RAPA) in older adults with Mild Cognitive Impairment (MCI) or early Alzheimer's disease (AD) and investigate associated safety, tolerability, target engagement, cognition, and functional status as initial proof-of-concept study

mild cognitive impairment
galantamine
alzheimer's disease
rivastigmine
cognitive impairment
  • 0 views
  • 25 Jan, 2021
  • 1 location
Evolution of Memory Related Activity

The purpose of this study is to begin the process of validating fMRI (functional magnetic resonance imaging) as a biomarker for use in clinical trials and longitudinal studies of clinical progression in mild cognitive impairment (MCI) and Alzheimer's disease (AD).

alzheimer's disease
depression
cognitive impairment
mild cognitive impairment
  • 48 views
  • 07 Nov, 2020
  • 1 location
ADDIA Proof-of-Performance Clinical Study

(AD): 200 patients with mild AD, 200 patients with moderate-to-severe AD, 200 patients with non-Alzheimer's neurodegenerative diseases (NAD), 200 controls (healthy as compared to

parkinsonism
antipsychotic agents
electroencephalogram
behavioral disorder
SPECT Scan
  • 314 views
  • 24 Jan, 2021
  • 13 locations
Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol

Since its launch in 2004, the overarching aim of the Alzheimer's Disease Neuroimaging Initiative (ADNI) has been realized in informing the design of therapeutic trials in AD. ADNI3 continues the previously funded ADNI-1, ADNI-GO, and ADNI-2 studies that have been combined public/private collaborations between academia and industry to determine the …

stroke
mental state examination
alzheimer's disease
depression
cholinesterase
  • 1043 views
  • 26 Jan, 2021
  • 59 locations
Gait Analysis by Induced Disorientation in a VR Environment

The aim of the study is to investigate whether the effect of disorientation on physical motion and gait among dementia patients, can be reliably measured in a laboratory environment, by means of a virtual reality (VR) experimental setup.

dementia
  • 0 views
  • 25 Jan, 2021
  • 2 locations
Cognition and NeuroImaging in neuroDegenerative Disorders (CogNID)

This prospective study aims: to compare cognitive performance in different clinical groups of participants with mild cognitive impairment (MCI) or mild dementia [Alzheimer's

  • 0 views
  • 22 Jan, 2021
  • 2 locations
Atlas of Retinal Imaging in Alzheimer's Study

The Atlas of Retinal Imaging in Alzheimer's (ARIAS) study is a 5-year study examining the natural history of retinal imaging biomarkers associated with disease risk, disease burden, and disease progression in Alzheimer's disease (AD). The objective of this project is to create a 'gold standard' reference database of structural anatomic …

mild cognitive impairment
alzheimer's disease
depression
cognitive assessment
cognitive impairment
  • 0 views
  • 25 Jan, 2021
  • 4 locations
Longitudinal Study for the Characterization of the Phases of Subjective Perception of Cognitive Decline and Mild Cognitive Impairment of Alzheimer's Disease.

MCI and mild dementia due to AD. The present study has two main objectives that are: To characterize from a cognitive and biomarker (when available) point of view persons with

mental deterioration
mild cognitive impairment
senile plaques
cognitive disorder
alzheimer's disease
  • 32 views
  • 24 Jan, 2021
  • 1 location