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Found 61 clinical trials
The PREVENTION Trial: Precision Recommendations to Optimize Neurocognition

based on three categories: 1) a diagnosis of mild AD according to criteria established by the National Institute of Neurological and Communicative Disorders and Stroke (AD and Related Disorders

  • 0 views
  • 23 Jan, 2021
  • 1 location
Drug Reduction in Older Patients: The DROP Trial

: mild dementia, delirium, falls, loss of urine, and unintentional weight loss. The investigators' innovative, patient-centered Drug Reduction in Older Patients (DROP) procedure has significant potential

  • 2 views
  • 26 Jan, 2021
  • 1 location
Using Exercise and Electrical Brain Stimulation to Improve Memory in Dementia

Mild cognitive impairment and Alzheimer's disease are conditions that involve memory difficulties. Transcranial direct current stimulation is a type of brain stimulation. It may help improve these memory difficulties. However, it works better on active brain areas. This study looks at if combining exercise and applying current to important parts …

mini-mental state examination
neurocognitive disorders
brain stimulation
mental state examination
vascular disease
  • 5 views
  • 23 Jan, 2021
  • 1 location
Music Therapy Experiences in Patients With Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)

This study compares different music therapy (MT) experiences and their impact on memory and language in patients with Alzheimer's disease and Mild Cognitive Impairment. The 12-month study will assess the role of common experiences involving familiar music and other pleasant events (blinded control) to benefit cognition and measure the quality …

  • 0 views
  • 26 Jan, 2021
  • 2 locations
Imaging Inflammation in Alzheimer's Disease With 11C-ER176

This study is being done to learn about inflammation in the brain of those with Alzheimer's disease (AD). The purpose of this study is to determine if 11C-ER176 is able to accurately measure inflammation in patients with Alzheimer's disease. Both patients (with either mild cognitive impairment (MCI) or Alzheimer's disease) …

florbetaben
amyloid
alzheimer's disease
cognitive impairment
mild cognitive impairment
  • 6 views
  • 25 Jan, 2021
  • 1 location
Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease

Alzheimer's disease (AD) is the leading neurodegenerative disease of aging characterized by multiple cognitive impairments. Given the recent failures of disease-modifying drugs, the current focus is on preventing or mitigating synaptic damage that correlates with cognitive decline in AD patients. Transcranial Direct Current Stimulation (tDCS) is a safe, non-invasive, non-painful …

neurodegenerative disorders
positron emission tomography
amyloid
cognitive decline
neuropsychological test
  • 0 views
  • 24 Jan, 2021
  • 1 location
SEMA4D Blockade Safety and Brain Metabolic Activity in Alzheimer's Disease (AD)

To investigate safety, tolerability, the effects on cognition and brain metabolism of pepinemab in early AD dementia (early AD) subjects.

positron emission tomography
mini-mental state examination
amyloid
rivastigmine
donepezil
  • 7 views
  • 25 Jan, 2021
  • 14 locations
Coaching for Cognition in Alzheimer's (COCOA)

One major study objective is, using 2 study arms (data-driven health coaching plus RC vs. RC only), to evaluate the efficacy of data-driven health coaching. 'RC only' will serve as the control group. Participants will be enrolled in the trial on the basis of an existence of objective cognitive impairment …

alzheimer's disease
cognitive impairment
cognitive training
mild cognitive impairment
dementia
  • 33 views
  • 22 Jan, 2021
  • 1 location
Microglial Activation Positron Emission Tomography (PET) Brain Imaging in Multiple Sclerosis and Alzheimer's Disease

The specific aims of the study are: Primary: To determine the presence and regional distribution of microglial activation, as assessed by Fluorine-18 (18F) labeled "Peripheral Benzodiazepine Receptor 06" (PBR06) -PET, in subjects with active Relapsing Remitting Multiple Sclerosis (RRMS), Secondary Progressive Multiple Sclerosis (SPMS), and Alzheimer's Disease (AD) as compared …

positron emission tomography
mini-mental state examination
fatigue
relapsing multiple sclerosis
disease or disorder
  • 14 views
  • 26 Jan, 2021
  • 1 location
Stabilized Whole Rice Bran (SWRB) for Mild to Moderate Atopic Dermatitis

This clinical trial serves to look at the effectiveness of SWRB for the treatment of mild to moderate Atopic Dermatitis in patients below the age of 18. Atopic Dermatitis (AD) is a common condition seen in dermatology, paediatric and primary care clinics in Malaysia. AD poses a significant biopsychosocial burden …

  • 0 views
  • 26 Jan, 2021
  • 1 location