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Found 60 clinical trials
Effects of Sulforaphane in Patients With Prodromal to Mild Alzheimer's Disease

In this proposed study, the investigators will evaluate the efficacy, safety and related mechanism of sulforaphane in treatment of Alzheimer's disease (AD). The study will recruit 160 AD patients, and then these patients will be randomized to sulforaphane group or placebo group (80 patients per arm) for 24 weeks clinic …

cognitive assessment
alzheimer's disease
mini-mental state examination
stroke
mental state examination
  • 0 views
  • 25 Jan, 2021
  • 1 location
Clinical Trial to Determine Tolerable Dosis of Vorinostat in Patients With Mild Alzheimer Disease

This Clinical Trial is an open, non-randomized Phase Ib study to determine the maximal tolerable dose (MTD) of Vorinostat in Alzheimer disease (AD) patients between (including) 55 and 90 years with mild symptoms. The MTD in this study is defined as the dose that leads to maximum toxicity with Common …

mini-mental state examination
mental state examination
  • 25 views
  • 23 Jan, 2021
  • 4 locations
Nature Video to Improve Older Adult Health: A Feasibility Study.

adults diagnosed with mild cognitive impairment (MCI) or mild dementia. Objectives/Purpose: The primary purpose of this study is to assess the feasibility of providing an immersive nature-based

dementia
mild dementia
  • 5 views
  • 26 Jan, 2021
  • 2 locations
An Advance Care Planning Programme for Persons With Early Stage Dementia or Mild Cognitive Impairment in the Community

Advance care planning (ACP) has been widely advocated for persons with early stage dementia (PWEDs) and persons with mild cognitive impairment (MCI). This proposed study attempts to promote the uptake of ACP for this population and their family caregivers in the community and to examine the effects of an ACP …

dementia
  • 0 views
  • 25 Jan, 2021
  • 4 locations
A Study to Evaluate Safety and Tolerability of Different Doses and Efficacy of PQ912 in Subjects With MCI and Mild AD

glutaminyl cyclase enzyme, in 250 subjects with mild cognitive impairment and mild dementia due to Alzheimer 's Disease.

  • 0 views
  • 02 Feb, 2021
  • 10 locations
Anti-viral Therapy in Alzheimer's Disease

Anti-viral therapy in Alzheimer's disease will investigate the efficacy of treating patients with mild Alzheimer's disease with the U.S.A marketed generic anti-viral drug Valtrex (valacyclovir

amyloid
memantine
cholinesterase
alzheimer's disease
mini-mental state examination
  • 20 views
  • 03 Feb, 2021
  • 3 locations
Light Metabolic Syndrome and Alzheimer's Disease

To test the long term effect of a light treatment on cognition, sleep and metabolism in patients with Mild cognitive impairment (MCI) or mild Alzheimer's disease or related dementia (ADRD

alzheimer's disease
mild cognitive impairment
mini-mental state examination
dementia
cognitive impairment
  • 4 views
  • 29 Jan, 2021
  • 2 locations
Deferiprone to Delay Dementia (The 3D Study)

Alzheimer's Disease (mAD). In this phase 2 study, the investigators aim to determine whether Deferiprone (15 mg/kg BID orally) slows cognitive decline in Alzheimer's patients. As secondary outcomes, safety

neuropsychological test
amyloid
alzheimer's disease
amyloidosis
mini-mental state examination
  • 76 views
  • 23 Jan, 2021
  • 9 locations
The Long-term Impact of a Light Intervention on Sleep and Cognition in Mild Cognitive Impairment

To investigate the impact of a long-term light treatment intervention on sleep physiology and memory in mild cognitively impaired and mild Alzheimer's disease patients living at home. The goal

cognitive assessment
alzheimer's disease
mild cognitive impairment
depression
dementia
  • 6 views
  • 28 Jan, 2021
  • 3 locations
DAOIB Combined With tDCS for Early-phase Dementia

This is a 24-week randomized, double-blind, placebo-controlled trial. We will enroll patients with aMCI or mild AD. All patients will receive 2 weeks of tDCS (5 sessions per week, 10 sessions in

  • 0 views
  • 11 Feb, 2021
  • 1 location